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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST2H2BE All Species: 37.58
Human Site: S88 Identified Species: 75.15
UniProt: Q16778 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16778 NP_003519.1 126 13920 S88 L A H Y N K R S T I T S R E I
Chimpanzee Pan troglodytes XP_518302 152 16759 S114 L A H Y N K R S T I T S R E I
Rhesus Macaque Macaca mulatta XP_001090500 154 17046 S116 L A H Y N K R S T I T S R E I
Dog Lupus familis XP_545412 137 15110 S88 L A H Y N K R S T I T S R E I
Cat Felis silvestris
Mouse Mus musculus P10854 126 13918 S88 L A H Y N K R S T I T S R E I
Rat Rattus norvegicus Q00715 125 13972 T88 A H Y N K R S T I T S R E I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515176 126 13930 S88 L A H Y N K R S T I T S R E I
Chicken Gallus gallus P0C1H4 126 13932 S88 L A H Y N K R S T I T S R E I
Frog Xenopus laevis P02281 126 13916 S88 L A H Y N K R S T I T S R E I
Zebra Danio Brachydanio rerio Q6PC60 126 13930 S88 L A H Y N K R S T I T S R E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P04255 122 13482 I86 H Y N K R S T I S S R E I Q T
Sea Urchin Strong. purpuratus P02289 124 13598 I88 Q Y N K K S T I S S R E I Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 81.1 90.5 N.A. 98.4 96 N.A. 99.2 96 94.4 94.4 N.A. N.A. N.A. 80.1 78.5
Protein Similarity: 100 82.8 81.8 91.9 N.A. 99.2 97.6 N.A. 99.2 97.6 98.4 97.6 N.A. N.A. N.A. 88 85.7
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 100 100 100 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 100 100 100 100 N.A. N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 17 9 75 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 9 9 75 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 17 9 75 0 0 17 9 75 % I
% Lys: 0 0 0 17 17 75 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 9 75 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 9 % Q
% Arg: 0 0 0 0 9 9 75 0 0 0 17 9 75 0 0 % R
% Ser: 0 0 0 0 0 17 9 75 17 17 9 75 0 0 0 % S
% Thr: 0 0 0 0 0 0 17 9 75 9 75 0 0 0 17 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 9 75 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _