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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
13.64
Human Site:
S473
Identified Species:
25
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
S473
A
S
G
S
P
F
K
S
V
T
L
E
D
G
K
Chimpanzee
Pan troglodytes
XP_508682
604
67038
S473
A
S
G
S
P
F
K
S
V
T
L
E
D
G
K
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
I421
L
E
D
G
K
T
F
I
P
G
Q
G
N
N
A
Dog
Lupus familis
XP_848770
604
67177
S473
A
S
G
S
P
F
K
S
V
T
L
E
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
S473
A
S
G
S
P
F
K
S
V
T
L
E
D
G
R
Rat
Rattus norvegicus
P13697
572
63984
P438
A
S
G
S
P
F
D
P
V
T
L
P
D
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
G434
D
P
V
T
L
P
D
G
R
T
L
Y
P
G
Q
Chicken
Gallus gallus
NP_989634
557
61982
G433
D
P
V
T
L
P
N
G
K
T
L
Y
P
G
Q
Frog
Xenopus laevis
NP_001088519
613
67458
K482
A
S
G
S
P
F
S
K
V
T
L
A
N
G
Q
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
K472
A
S
G
S
P
F
K
K
V
T
L
A
D
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
P453
A
S
G
S
P
F
D
P
F
T
L
P
N
G
K
Poplar Tree
Populus trichocarpa
P34105
591
65205
G465
E
A
Y
T
W
T
K
G
K
A
I
F
A
S
G
Maize
Zea mays
P16243
636
69805
G510
Q
A
Y
T
W
S
Q
G
R
S
I
F
A
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
0
93.3
N.A.
93.3
73.3
N.A.
20
20
66.6
80
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
80
N.A.
33.3
33.3
80
86.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
16
0
0
0
0
0
0
0
8
0
16
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
0
24
0
0
0
0
0
47
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
0
31
0
0
0
% E
% Phe:
0
0
0
0
0
62
8
0
8
0
0
16
0
0
0
% F
% Gly:
0
0
62
8
0
0
0
31
0
8
0
8
0
77
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
16
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
47
16
16
0
0
0
0
0
24
% K
% Leu:
8
0
0
0
16
0
0
0
0
0
77
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
24
8
0
% N
% Pro:
0
16
0
0
62
16
0
16
8
0
0
16
16
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
24
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
31
% R
% Ser:
0
62
0
62
0
8
8
31
0
8
0
0
0
16
0
% S
% Thr:
0
0
0
31
0
16
0
0
0
77
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
54
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _