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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
38.48
Human Site:
S563
Identified Species:
70.56
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
S563
A
Y
K
H
N
L
A
S
Y
Y
P
E
P
K
D
Chimpanzee
Pan troglodytes
XP_508682
604
67038
S563
A
Y
K
H
N
L
A
S
Y
Y
P
E
P
K
D
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
S501
A
Y
K
H
N
L
A
S
Y
Y
P
E
P
K
D
Dog
Lupus familis
XP_848770
604
67177
S563
A
Y
K
H
N
L
A
S
Y
Y
P
E
P
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
S563
A
Y
K
H
N
L
A
S
Y
Y
P
E
P
K
D
Rat
Rattus norvegicus
P13697
572
63984
T528
A
Y
K
E
K
M
A
T
V
Y
P
E
P
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
S518
A
Y
Q
K
N
L
A
S
I
H
P
E
P
P
N
Chicken
Gallus gallus
NP_989634
557
61982
T517
A
Y
R
N
N
T
A
T
T
Y
P
Q
P
E
D
Frog
Xenopus laevis
NP_001088519
613
67458
S572
A
Y
K
N
N
M
A
S
W
Y
P
E
P
A
D
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
S562
A
Y
K
Q
G
I
A
S
W
Y
P
E
P
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
T539
V
G
E
Y
A
Y
D
T
G
M
A
S
K
Y
P
Poplar Tree
Populus trichocarpa
P34105
591
65205
K546
P
P
L
S
N
I
R
K
I
S
V
Q
I
A
A
Maize
Zea mays
P16243
636
69805
H595
S
I
R
K
I
S
A
H
I
A
A
A
V
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
60
53.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
80
86.6
93.3
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
0
0
8
0
85
0
0
8
16
8
0
24
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
62
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
0
70
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
39
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
16
0
0
24
0
0
0
8
0
0
% I
% Lys:
0
0
62
16
8
0
0
8
0
0
0
0
8
47
0
% K
% Leu:
0
0
8
0
0
47
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
16
70
0
0
0
0
0
0
0
0
0
16
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
77
0
77
8
8
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
16
0
8
0
% Q
% Arg:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
8
0
62
0
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
24
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% W
% Tyr:
0
77
0
8
0
8
0
0
39
70
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _