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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
30.61
Human Site:
T161
Identified Species:
56.11
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
T161
R
P
R
G
L
F
I
T
I
H
D
K
G
H
L
Chimpanzee
Pan troglodytes
XP_508682
604
67038
T161
R
P
R
G
L
F
I
T
I
H
D
K
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
L147
M
G
I
P
V
G
K
L
A
L
Y
T
A
C
G
Dog
Lupus familis
XP_848770
604
67177
T161
R
P
R
G
L
F
I
T
I
H
D
K
G
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
T161
R
P
R
G
L
F
I
T
I
H
D
K
G
H
I
Rat
Rattus norvegicus
P13697
572
63984
L159
D
G
E
R
I
L
G
L
G
D
L
G
C
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
G158
D
L
G
C
N
G
M
G
I
P
V
G
K
L
A
Chicken
Gallus gallus
NP_989634
557
61982
G157
D
L
G
C
Y
G
M
G
I
P
V
G
K
L
A
Frog
Xenopus laevis
NP_001088519
613
67458
T170
R
P
R
G
L
F
I
T
I
H
D
K
G
H
I
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
T160
R
P
R
G
L
F
I
T
I
H
D
K
G
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
V163
Q
N
V
K
A
I
V
V
T
D
G
E
R
I
L
Poplar Tree
Populus trichocarpa
P34105
591
65205
S163
R
P
Q
G
L
Y
I
S
L
K
E
K
G
K
V
Maize
Zea mays
P16243
636
69805
S208
R
P
Q
G
L
Y
V
S
L
K
D
K
G
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
6.6
6.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
13.3
N.A.
13.3
13.3
100
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
16
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
24
0
0
0
0
0
0
0
0
16
54
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
16
62
0
24
8
16
8
0
8
24
62
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
47
0
0
0
47
0
% H
% Ile:
0
0
8
0
8
8
54
0
62
0
0
0
0
8
24
% I
% Lys:
0
0
0
8
0
0
8
0
0
16
0
62
16
16
0
% K
% Leu:
0
16
0
0
62
8
0
16
16
8
8
0
0
16
31
% L
% Met:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
62
0
8
0
0
0
0
0
16
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
62
0
47
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
47
8
0
0
8
0
0
0
% T
% Val:
0
0
8
0
8
0
16
8
0
0
16
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
16
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _