KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
31.52
Human Site:
T232
Identified Species:
57.78
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
T232
P
V
L
L
D
V
G
T
N
N
E
E
L
L
R
Chimpanzee
Pan troglodytes
XP_508682
604
67038
T232
P
V
L
L
D
V
G
T
N
N
E
E
L
L
R
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
L214
D
K
F
G
I
N
C
L
I
Q
F
E
D
F
A
Dog
Lupus familis
XP_848770
604
67177
T232
P
V
L
L
D
V
G
T
N
N
E
E
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
T232
P
V
L
L
D
V
G
T
N
N
E
E
L
L
R
Rat
Rattus norvegicus
P13697
572
63984
F228
Y
D
A
F
L
D
E
F
M
E
A
A
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
R225
F
M
E
A
V
T
S
R
Y
G
M
N
C
L
I
Chicken
Gallus gallus
NP_989634
557
61982
S224
F
M
E
A
V
T
S
S
Y
G
M
N
C
L
I
Frog
Xenopus laevis
NP_001088519
613
67458
T241
P
V
L
L
D
V
G
T
D
N
E
A
L
L
N
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
T231
P
V
L
L
D
V
G
T
D
N
Q
T
L
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
S233
D
K
R
D
R
S
E
S
Y
D
E
L
I
D
E
Poplar Tree
Populus trichocarpa
P34105
591
65205
T234
P
V
T
I
D
V
G
T
N
N
E
Q
L
L
K
Maize
Zea mays
P16243
636
69805
T279
P
I
T
I
D
V
G
T
N
N
E
F
L
L
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
6.6
6.6
80
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
13.3
20
86.6
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
73.3
66.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
93.3
80
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
0
0
0
0
8
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
16
0
0
% C
% Asp:
16
8
0
8
62
8
0
0
16
8
0
0
8
8
8
% D
% Glu:
0
0
16
0
0
0
16
0
0
8
62
39
0
0
8
% E
% Phe:
16
0
8
8
0
0
0
8
0
0
8
8
0
8
0
% F
% Gly:
0
0
0
8
0
0
62
0
0
16
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
8
0
0
0
8
0
0
0
8
0
16
% I
% Lys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
16
% K
% Leu:
0
0
47
47
8
0
0
8
0
0
0
8
62
77
0
% L
% Met:
0
16
0
0
0
0
0
0
8
0
16
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
47
62
0
16
0
0
16
% N
% Pro:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
31
% R
% Ser:
0
0
0
0
0
8
16
16
0
0
0
0
8
8
0
% S
% Thr:
0
0
16
0
0
16
0
62
0
0
0
8
0
0
0
% T
% Val:
0
54
0
0
16
62
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _