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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
30.61
Human Site:
T459
Identified Species:
56.11
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
T459
A
E
K
C
Y
R
V
T
E
G
R
G
I
F
A
Chimpanzee
Pan troglodytes
XP_508682
604
67038
T459
A
E
K
C
Y
R
V
T
E
G
R
G
I
F
A
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
S407
R
G
I
F
A
S
G
S
P
F
K
S
V
T
L
Dog
Lupus familis
XP_848770
604
67177
T459
A
E
K
C
Y
R
V
T
E
G
R
G
I
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
T459
A
E
K
C
Y
R
V
T
E
G
R
G
I
F
A
Rat
Rattus norvegicus
P13697
572
63984
T424
A
E
E
C
Y
K
V
T
K
G
R
A
I
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
F420
F
T
E
G
R
G
I
F
A
S
G
S
P
F
D
Chicken
Gallus gallus
NP_989634
557
61982
F419
Y
T
E
G
R
G
I
F
A
S
G
S
P
F
D
Frog
Xenopus laevis
NP_001088519
613
67458
T468
A
E
Q
C
Y
Q
L
T
E
G
R
G
I
F
A
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
T458
A
E
Q
C
Y
T
L
T
E
G
R
G
I
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
T439
A
E
Q
A
Y
T
H
T
N
G
Q
C
V
F
A
Poplar Tree
Populus trichocarpa
P34105
591
65205
Q451
A
L
S
N
P
T
S
Q
S
E
C
T
A
Q
E
Maize
Zea mays
P16243
636
69805
H496
S
L
S
N
P
T
S
H
S
E
C
T
A
E
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
0
100
N.A.
100
73.3
N.A.
6.6
6.6
80
80
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
20
100
N.A.
100
93.3
N.A.
20
20
100
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
8
8
0
0
0
16
0
0
8
16
0
62
% A
% Cys:
0
0
0
54
0
0
0
0
0
0
16
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
0
62
24
0
0
0
0
0
47
16
0
0
0
8
8
% E
% Phe:
8
0
0
8
0
0
0
16
0
8
0
0
0
77
0
% F
% Gly:
0
8
0
16
0
16
8
0
0
62
16
47
0
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
0
0
54
0
0
% I
% Lys:
0
0
31
0
0
8
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
16
0
0
0
0
16
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
8
0
0
0
16
0
0
% P
% Gln:
0
0
24
0
0
8
0
8
0
0
8
0
0
8
8
% Q
% Arg:
8
0
0
0
16
31
0
0
0
0
54
0
0
0
0
% R
% Ser:
8
0
16
0
0
8
16
8
16
16
0
24
0
0
0
% S
% Thr:
0
16
0
0
0
31
0
62
0
0
0
16
0
8
0
% T
% Val:
0
0
0
0
0
0
39
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _