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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
32.12
Human Site:
T581
Identified Species:
58.89
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
T581
F
V
R
S
L
V
Y
T
P
D
Y
D
S
F
T
Chimpanzee
Pan troglodytes
XP_508682
604
67038
T581
F
V
R
S
L
V
Y
T
P
D
Y
D
S
F
T
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
T519
F
V
R
S
L
V
Y
T
P
D
Y
D
S
F
T
Dog
Lupus familis
XP_848770
604
67177
T581
F
V
R
S
L
V
Y
T
P
D
Y
D
S
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
T581
F
V
K
S
L
I
Y
T
P
D
Y
D
S
F
S
Rat
Rattus norvegicus
P13697
572
63984
S546
F
V
S
S
Q
M
Y
S
T
N
Y
D
Q
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
S536
F
I
R
A
Q
I
Y
S
T
D
Y
D
E
F
L
Chicken
Gallus gallus
NP_989634
557
61982
S535
F
I
R
S
Q
M
Y
S
T
D
Y
N
S
F
V
Frog
Xenopus laevis
NP_001088519
613
67458
S590
F
V
R
S
L
I
Y
S
P
D
Y
D
S
S
T
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
N580
F
I
L
S
H
V
Y
N
S
D
Y
D
S
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
K557
D
M
E
A
Y
V
R
K
C
V
Y
D
Y
E
Y
Poplar Tree
Populus trichocarpa
P34105
591
65205
L564
A
K
A
Y
E
L
G
L
A
T
R
L
P
R
P
Maize
Zea mays
P16243
636
69805
L613
E
L
G
L
A
T
R
L
P
P
P
S
D
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
100
100
N.A.
80
40
N.A.
46.6
53.3
80
66.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
73.3
80
93.3
73.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
16
8
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
70
0
77
8
0
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
77
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% F
% Gly:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
24
0
0
0
24
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
47
8
0
16
0
0
0
8
0
8
16
% L
% Met:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
54
8
8
0
8
0
8
% P
% Gln:
0
0
0
0
24
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
54
0
0
0
16
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
8
70
0
0
0
31
8
0
0
8
62
8
8
% S
% Thr:
0
0
0
0
0
8
0
39
24
8
0
0
0
0
47
% T
% Val:
0
54
0
0
0
47
0
0
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
77
0
0
0
85
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _