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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
31.21
Human Site:
T593
Identified Species:
57.22
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
T593
S
F
T
L
D
S
Y
T
W
P
K
E
A
M
N
Chimpanzee
Pan troglodytes
XP_508682
604
67038
T593
S
F
T
L
D
S
Y
T
W
P
K
E
A
M
N
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
T531
S
F
T
L
D
S
Y
T
W
P
K
E
A
M
N
Dog
Lupus familis
XP_848770
604
67177
T593
S
F
T
L
D
S
Y
T
W
P
K
E
A
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
S593
S
F
S
L
D
T
Y
S
W
P
K
E
A
M
S
Rat
Rattus norvegicus
P13697
572
63984
S558
Q
I
L
P
D
C
Y
S
W
P
E
E
V
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
S548
E
F
L
A
D
S
Y
S
W
P
E
E
A
A
R
Chicken
Gallus gallus
NP_989634
557
61982
T547
S
F
V
A
D
S
Y
T
W
P
E
D
A
M
K
Frog
Xenopus laevis
NP_001088519
613
67458
H602
S
S
T
I
D
S
Y
H
W
P
T
K
A
M
E
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
S592
S
F
T
L
D
S
Y
S
W
P
K
D
A
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
P569
Y
E
Y
E
S
F
T
P
D
Y
Y
D
W
P
T
Poplar Tree
Populus trichocarpa
P34105
591
65205
K576
P
R
P
E
N
L
V
K
H
A
E
S
C
M
Y
Maize
Zea mays
P16243
636
69805
N625
D
L
V
K
Y
A
E
N
C
M
Y
T
P
V
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
100
100
N.A.
73.3
33.3
N.A.
53.3
66.6
60
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
66.6
80
73.3
93.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
8
0
0
0
8
0
0
70
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
77
0
0
0
8
0
0
24
0
0
0
% D
% Glu:
8
8
0
16
0
0
8
0
0
0
31
54
0
0
8
% E
% Phe:
0
62
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
47
8
0
0
24
% K
% Leu:
0
8
16
47
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
70
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
31
% N
% Pro:
8
0
8
8
0
0
0
8
0
77
0
0
8
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
62
8
8
0
8
62
0
31
0
0
0
8
0
0
8
% S
% Thr:
0
0
47
0
0
8
8
39
0
0
8
8
0
0
8
% T
% Val:
0
0
16
0
0
0
8
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
77
0
0
0
8
0
0
% W
% Tyr:
8
0
8
0
8
0
77
0
0
8
16
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _