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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ME3
All Species:
39.09
Human Site:
Y535
Identified Species:
71.67
UniProt:
Q16798
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16798
NP_001014811.1
604
67068
Y535
H
L
S
Q
G
R
L
Y
P
P
L
S
T
I
R
Chimpanzee
Pan troglodytes
XP_508682
604
67038
Y535
H
L
S
Q
G
R
L
Y
P
P
L
S
T
I
R
Rhesus Macaque
Macaca mulatta
XP_001103502
542
60590
Y473
H
L
S
Q
G
R
L
Y
P
P
L
S
T
I
R
Dog
Lupus familis
XP_848770
604
67177
Y535
H
L
S
Q
G
R
L
Y
P
P
L
S
T
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF3
604
67162
Y535
H
L
S
Q
G
R
L
Y
P
P
L
S
T
I
R
Rat
Rattus norvegicus
P13697
572
63984
Y500
H
L
E
E
G
R
L
Y
P
P
L
N
T
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512855
562
62388
Y490
H
L
E
E
G
R
L
Y
P
P
L
H
T
I
Q
Chicken
Gallus gallus
NP_989634
557
61982
Y489
N
L
Q
E
G
R
L
Y
P
P
L
V
T
I
Q
Frog
Xenopus laevis
NP_001088519
613
67458
Y544
N
L
A
E
G
R
L
Y
P
P
L
S
S
I
R
Zebra Danio
Brachydanio rerio
NP_001082825
603
66722
Y534
H
L
A
E
G
R
L
Y
P
P
L
K
T
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780686
581
64710
E511
V
T
Q
A
H
L
D
E
G
R
V
Y
P
P
L
Poplar Tree
Populus trichocarpa
P34105
591
65205
A518
V
H
D
D
M
L
L
A
A
A
E
A
L
A
G
Maize
Zea mays
P16243
636
69805
A567
M
L
L
A
A
S
K
A
L
A
D
Q
A
T
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.5
96
N.A.
93.8
67.3
N.A.
68.8
67.3
75
75.8
N.A.
N.A.
N.A.
N.A.
58.7
Protein Similarity:
100
99.6
89.5
97.5
N.A.
96.5
81.6
N.A.
81.9
81.9
87.9
87.2
N.A.
N.A.
N.A.
N.A.
74.3
P-Site Identity:
100
100
100
100
N.A.
100
80
N.A.
73.3
66.6
73.3
80
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
86.6
100
93.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
46.5
45.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
65.4
63.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
16
8
0
0
16
8
16
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
16
39
0
0
0
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
77
0
0
0
8
0
0
0
0
0
8
% G
% His:
62
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% K
% Leu:
0
85
8
0
0
16
85
0
8
0
77
0
8
0
8
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
77
77
0
0
8
8
0
% P
% Gln:
0
0
16
39
0
0
0
0
0
0
0
8
0
0
24
% Q
% Arg:
0
0
0
0
0
77
0
0
0
8
0
0
0
0
62
% R
% Ser:
0
0
39
0
0
8
0
0
0
0
0
47
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
70
8
0
% T
% Val:
16
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _