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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKG1 All Species: 30.61
Human Site: S251 Identified Species: 56.11
UniProt: Q16816 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16816 NP_006204.1 387 45024 S251 S G N Y Q F G S P E W D D Y S
Chimpanzee Pan troglodytes XP_001153926 382 44180 S246 S G N Y Q F G S P E W D D Y S
Rhesus Macaque Macaca mulatta XP_001089751 387 44961 S251 S G N Y Q F G S P E W D D Y S
Dog Lupus familis XP_546902 530 60068 S394 S G N Y Q F G S P E W D D Y S
Cat Felis silvestris
Mouse Mus musculus P07934 388 44941 S251 D G K Y Q F G S P E W D D Y S
Rat Rattus norvegicus P13286 388 44996 S251 D G K Y Q F G S P E W D D Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI0 479 54184 A296 D C L K K F N A R R K L K G A
Frog Xenopus laevis Q9DG02 475 53914 N294 V D C L K K F N A R R K L K G
Zebra Danio Brachydanio rerio Q6DGS3 554 62366 T372 S T E S A N T T I E D E D L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 T339 S T D S S S T T L E D D D I K
Honey Bee Apis mellifera XP_623113 415 47613 S277 V D P K K R I S I K E A L E H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787539 414 46709 S259 E G R Y R F G S P E W D D I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 T306 E G K L D L E T S P W P T I S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.2 98.9 69.2 N.A. 93.3 93.8 N.A. N.A. 31.1 31.7 29.4 N.A. 27.7 51.5 N.A. 49.5
Protein Similarity: 100 94.5 99.7 70.9 N.A. 97.6 97.9 N.A. N.A. 46.7 46.9 42.2 N.A. 44.1 68.4 N.A. 64.9
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. 6.6 0 20 N.A. 26.6 6.6 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. N.A. 26.6 13.3 33.3 N.A. 40 20 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 8 0 0 8 0 0 8 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 16 8 0 8 0 0 0 0 0 16 62 70 0 0 % D
% Glu: 16 0 8 0 0 0 8 0 0 70 8 8 0 8 0 % E
% Phe: 0 0 0 0 0 62 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 62 0 0 0 0 54 0 0 0 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 8 0 16 0 0 0 0 24 0 % I
% Lys: 0 0 24 16 24 8 0 0 0 8 8 8 8 8 16 % K
% Leu: 0 0 8 16 0 8 0 0 8 0 0 8 16 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 31 0 0 8 8 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 54 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 8 8 0 0 8 16 8 0 0 0 0 % R
% Ser: 47 0 0 16 8 8 0 62 8 0 0 0 0 0 62 % S
% Thr: 0 16 0 0 0 0 16 24 0 0 0 0 8 0 0 % T
% Val: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 % W
% Tyr: 0 0 0 54 0 0 0 0 0 0 0 0 0 47 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _