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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKG1 All Species: 23.64
Human Site: S300 Identified Species: 43.33
UniProt: Q16816 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16816 NP_006204.1 387 45024 S300 V E E V R H F S P R G K F K V
Chimpanzee Pan troglodytes XP_001153926 382 44180 S295 V E E V R H F S P R G K F K V
Rhesus Macaque Macaca mulatta XP_001089751 387 44961 S300 V E E V R H F S P R G K F K V
Dog Lupus familis XP_546902 530 60068 S443 V E E V R H F S P R G K F K V
Cat Felis silvestris
Mouse Mus musculus P07934 388 44941 S300 V E E V R H F S P R G K F K V
Rat Rattus norvegicus P13286 388 44996 S300 V E E V R H F S P R G K F K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI0 479 54184 A345 I E D E D V K A R K Q E I I K
Frog Xenopus laevis Q9DG02 475 53914 A343 I E D E D V K A R K Q E I I K
Zebra Danio Brachydanio rerio Q6DGS3 554 62366 A421 T C Q V I N K A R K Q E I I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 A388 G N S Q C S S A R R Q E I I K
Honey Bee Apis mellifera XP_623113 415 47613 N326 E L K A K S F N A R K R F Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787539 414 46709 N308 V P I G T T F N A R R K F K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 S355 I S D K P I N S A V L V R M K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.2 98.9 69.2 N.A. 93.3 93.8 N.A. N.A. 31.1 31.7 29.4 N.A. 27.7 51.5 N.A. 49.5
Protein Similarity: 100 94.5 99.7 70.9 N.A. 97.6 97.9 N.A. N.A. 46.7 46.9 42.2 N.A. 44.1 68.4 N.A. 64.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 20 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 40 40 40 N.A. 20 60 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 31 24 0 0 0 0 0 8 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 24 0 16 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 62 47 16 0 0 0 0 0 0 0 31 0 0 0 % E
% Phe: 0 0 0 0 0 0 62 0 0 0 0 0 62 0 0 % F
% Gly: 8 0 0 8 0 0 0 0 0 0 47 0 0 0 0 % G
% His: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % H
% Ile: 24 0 8 0 8 8 0 0 0 0 0 0 31 31 0 % I
% Lys: 0 0 8 8 8 0 24 0 0 24 8 54 0 54 39 % K
% Leu: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 0 0 0 8 8 16 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 8 0 0 0 47 0 0 0 0 0 0 % P
% Gln: 0 0 8 8 0 0 0 0 0 0 31 0 0 8 0 % Q
% Arg: 0 0 0 0 47 0 0 0 31 70 8 8 8 0 0 % R
% Ser: 0 8 8 0 0 16 8 54 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % T
% Val: 54 0 0 54 0 16 0 0 0 8 0 8 0 0 47 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _