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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKG1 All Species: 28.18
Human Site: Y291 Identified Species: 51.67
UniProt: Q16816 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16816 NP_006204.1 387 45024 Y291 A H P F F Q Q Y L V E E V R H
Chimpanzee Pan troglodytes XP_001153926 382 44180 Y286 A H P F F Q Q Y V V E E V R H
Rhesus Macaque Macaca mulatta XP_001089751 387 44961 Y291 A H P F F Q Q Y V V E E V R H
Dog Lupus familis XP_546902 530 60068 Y434 A H P F F Q Q Y V V E E V R H
Cat Felis silvestris
Mouse Mus musculus P07934 388 44941 Y291 A H P F F Q E Y V V E E V R H
Rat Rattus norvegicus P13286 388 44996 Y291 A H P F F Q E Y V V E E V R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI0 479 54184 T336 E S T E S S N T T I E D E D V
Frog Xenopus laevis Q9DG02 475 53914 T334 E S T E S S N T T I E D E D V
Zebra Danio Brachydanio rerio Q6DGS3 554 62366 V412 K Q A P N S S V Q T C Q V I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 N379 P A K T Y Q Q N I G N S Q C S
Honey Bee Apis mellifera XP_623113 415 47613 A317 L S R I S Q L A L E L K A K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787539 414 46709 T299 E H P F F Q Q T E V P I G T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 T346 E H P W M T D T K I S D K P I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.2 98.9 69.2 N.A. 93.3 93.8 N.A. N.A. 31.1 31.7 29.4 N.A. 27.7 51.5 N.A. 49.5
Protein Similarity: 100 94.5 99.7 70.9 N.A. 97.6 97.9 N.A. N.A. 46.7 46.9 42.2 N.A. 44.1 68.4 N.A. 64.9
P-Site Identity: 100 93.3 93.3 93.3 N.A. 86.6 86.6 N.A. N.A. 6.6 6.6 6.6 N.A. 13.3 13.3 N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 20 20 N.A. 26.6 26.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 8 8 0 0 0 0 8 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 24 0 16 0 % D
% Glu: 31 0 0 16 0 0 16 0 8 8 62 47 16 0 0 % E
% Phe: 0 0 0 54 54 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % G
% His: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 47 % H
% Ile: 0 0 0 8 0 0 0 0 8 24 0 8 0 8 8 % I
% Lys: 8 0 8 0 0 0 0 0 8 0 0 8 8 8 0 % K
% Leu: 8 0 0 0 0 0 8 0 16 0 8 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 16 8 0 0 8 0 0 0 8 % N
% Pro: 8 0 62 8 0 0 0 0 0 0 8 0 0 8 0 % P
% Gln: 0 8 0 0 0 70 47 0 8 0 0 8 8 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 47 0 % R
% Ser: 0 24 0 0 24 24 8 0 0 0 8 8 0 0 16 % S
% Thr: 0 0 16 8 0 8 0 31 16 8 0 0 0 8 8 % T
% Val: 0 0 0 0 0 0 0 8 39 54 0 0 54 0 16 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _