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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEP1B
All Species:
11.52
Human Site:
S688
Identified Species:
28.15
UniProt:
Q16820
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16820
NP_005916.2
701
79581
S688
K
Y
R
E
R
M
S
S
N
R
P
N
L
T
P
Chimpanzee
Pan troglodytes
XP_523904
701
79652
S688
K
Y
R
E
R
M
S
S
N
Q
P
N
L
T
P
Rhesus Macaque
Macaca mulatta
XP_001100668
701
79512
S688
K
Y
R
E
R
M
S
S
N
G
P
N
L
T
L
Dog
Lupus familis
XP_547619
691
78583
S678
R
Y
R
S
R
T
S
S
N
T
A
D
M
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61847
704
79530
A689
R
R
K
Y
R
K
K
A
R
A
N
T
A
A
M
Rat
Rattus norvegicus
P28826
704
79231
K688
T
R
R
K
Y
R
K
K
A
S
A
K
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511791
867
97753
G684
A
S
C
R
C
T
S
G
H
A
F
F
Y
T
G
Chicken
Gallus gallus
Q9DER7
1008
114873
R885
H
S
T
E
C
G
G
R
L
K
A
E
T
K
P
Frog
Xenopus laevis
NP_001091342
705
79893
G690
M
L
I
G
G
G
A
G
T
I
A
L
T
I
A
Zebra Danio
Brachydanio rerio
O57460
1022
115518
I958
A
D
C
G
Y
D
Y
I
E
L
Y
D
G
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.5
83.8
N.A.
77.2
77.1
N.A.
35.6
20.7
41.7
20.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98
90.3
N.A.
86.7
86.9
N.A.
51
34.8
59.4
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
46.6
N.A.
6.6
6.6
N.A.
13.3
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
26.6
13.3
N.A.
20
20
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
10
10
10
20
40
0
10
20
20
% A
% Cys:
0
0
20
0
20
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
0
0
0
20
0
0
10
% D
% Glu:
0
0
0
40
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
20
10
20
10
20
0
10
0
0
10
0
10
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
10
0
0
0
10
0
% I
% Lys:
30
0
10
10
0
10
20
10
0
10
0
10
0
10
0
% K
% Leu:
0
10
0
0
0
0
0
0
10
10
0
10
30
0
20
% L
% Met:
10
0
0
0
0
30
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
40
0
10
30
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
30
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
20
20
50
10
50
10
0
10
10
10
0
0
0
0
0
% R
% Ser:
0
20
0
10
0
0
50
40
0
10
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
20
0
0
10
10
0
10
30
50
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
40
0
10
20
0
10
0
0
0
10
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _