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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPP1 All Species: 30.91
Human Site: T180 Identified Species: 68
UniProt: Q16831 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16831 NP_003355.1 310 33934 T180 G K R V I R K T D L N K K L V
Chimpanzee Pan troglodytes XP_001152891 265 28949 D136 K R V I R K T D L N K K L V Q
Rhesus Macaque Macaca mulatta XP_001084656 310 33908 T180 G K R V I R K T D L N K K L V
Dog Lupus familis XP_537889 315 33991 T180 G K R V V Q R T D L D Q E L A
Cat Felis silvestris
Mouse Mus musculus P52624 311 34068 T181 G K R V I R N T N L D A Q L V
Rat Rattus norvegicus NP_001025196 312 34096 T182 G K R V T R N T S L D A Q L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506899 306 33807 T176 G K R V V R N T D L D E K L A
Chicken Gallus gallus XP_419026 313 34357 T183 G K T I I R S T N L D E E L A
Frog Xenopus laevis NP_001088941 316 35092 T186 D K V V V R K T E L H K E L A
Zebra Danio Brachydanio rerio XP_002664881 309 34120 T176 G K P V V R S T E L D K E L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651515 347 38658 A187 G K T I H R P A K L D K K L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.1 98.3 69.2 N.A. 79 80.4 N.A. 73.8 71.5 60.7 66.7 N.A. 47.5 N.A. N.A. N.A.
Protein Similarity: 100 84.8 99 85 N.A. 90 90 N.A. 84.5 83.3 80 80 N.A. 64.5 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 53.3 N.A. 66.6 60 N.A. 66.6 46.6 53.3 53.3 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 93.3 N.A. 86.6 73.3 N.A. 86.6 80 80 80 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 19 0 0 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 10 37 0 64 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 19 0 0 19 37 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 28 37 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 91 0 0 0 10 28 0 10 0 10 55 37 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 10 91 0 0 10 91 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 28 0 19 10 19 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 10 19 0 10 % Q
% Arg: 0 10 55 0 10 82 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 19 0 10 0 10 82 0 0 0 0 0 0 0 % T
% Val: 0 0 19 73 37 0 0 0 0 0 0 0 0 10 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _