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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR2 All Species: 15.15
Human Site: S501 Identified Species: 25.64
UniProt: Q16832 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16832 NP_001014796.1 855 96736 S501 F A P G E E E S G C S G V V K
Chimpanzee Pan troglodytes Q7YR43 909 100624 E545 A Y S G D Y M E P E K P G A P
Rhesus Macaque Macaca mulatta XP_001118206 855 96702 S501 F A P G E E E S G C S G V V K
Dog Lupus familis XP_536144 849 95798 S495 F A P G E E E S G C S G V V K
Cat Felis silvestris
Mouse Mus musculus Q62371 854 96464 S501 F A P G E E E S G C S G V V K
Rat Rattus norvegicus Q63474 910 101146 E546 A C S G D Y M E P E K P G A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 P550 L D P G K E E P A C S P A A K
Chicken Gallus gallus Q91987 818 91718 F452 I M L I I L K F G R H S K F G
Frog Xenopus laevis O73798 1358 153845 A812 A E K L G C S A S N F V F A R
Zebra Danio Brachydanio rerio XP_684261 892 101731 A537 S Q T S E D T A S T I T A S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 A375 Q L N N A Q D A G R G N L G N
Honey Bee Apis mellifera XP_392450 898 100991 L533 Y T S P T A K L N I A A T S N
Nematode Worm Caenorhab. elegans NP_508572 797 90284 Y468 M S P I I S D Y A E P D I S V
Sea Urchin Strong. purpuratus XP_001202828 913 103393 Y542 V S E S S R I Y A E P E N P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 99.3 96.4 N.A. 95.9 52.8 N.A. 80.1 27.1 21 74.5 N.A. 24.3 30.2 32.8 39.8
Protein Similarity: 100 66 99.5 97.8 N.A. 97.3 66.1 N.A. 85.8 42.8 34.3 82.6 N.A. 41.9 48.7 52 55
P-Site Identity: 100 6.6 100 100 N.A. 100 6.6 N.A. 46.6 6.6 0 13.3 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 13.3 N.A. 53.3 13.3 13.3 26.6 N.A. 33.3 20 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 29 0 0 8 8 0 22 22 0 8 8 15 29 0 % A
% Cys: 0 8 0 0 0 8 0 0 0 36 0 0 0 0 0 % C
% Asp: 0 8 0 0 15 8 15 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 8 0 36 36 36 15 0 29 0 8 0 0 0 % E
% Phe: 29 0 0 0 0 0 0 8 0 0 8 0 8 8 0 % F
% Gly: 0 0 0 50 8 0 0 0 43 0 8 29 15 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 0 15 15 0 8 0 0 8 8 0 8 0 0 % I
% Lys: 0 0 8 0 8 0 15 0 0 0 15 0 8 0 43 % K
% Leu: 8 8 8 8 0 8 0 8 0 0 0 0 8 0 0 % L
% Met: 8 8 0 0 0 0 15 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 8 8 0 8 8 0 15 % N
% Pro: 0 0 43 8 0 0 0 8 15 0 15 22 0 8 15 % P
% Gln: 8 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 15 0 0 0 0 8 % R
% Ser: 8 15 22 15 8 8 8 29 15 0 36 8 0 22 0 % S
% Thr: 0 8 8 0 8 0 8 0 0 8 0 8 8 0 8 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 8 29 29 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 15 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _