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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR2 All Species: 30.61
Human Site: S683 Identified Species: 51.79
UniProt: Q16832 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16832 NP_001014796.1 855 96736 S683 S S D V R T V S Y T N L K F M
Chimpanzee Pan troglodytes Q7YR43 909 100624 S735 A A Q G P T I S Y P M L L H V
Rhesus Macaque Macaca mulatta XP_001118206 855 96702 S683 S S N V P T V S Y T N L K F M
Dog Lupus familis XP_536144 849 95798 S677 S G N V P T V S Y A N L K F M
Cat Felis silvestris
Mouse Mus musculus Q62371 854 96464 S682 C S S D A T V S Y A N L K F M
Rat Rattus norvegicus Q63474 910 101146 S736 S D Q G P T I S Y P M L L H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 S741 A A S R P A V S Y V N L K F M
Chicken Gallus gallus Q91987 818 91718 T645 G N R P A E L T Q S Q M L H I
Frog Xenopus laevis O73798 1358 153845 S1104 N S G Q P T P S L K K M I Q M
Zebra Danio Brachydanio rerio XP_684261 892 101731 S721 L S N A P T V S Y S N L H H M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 A520 Q L E F L Q I A L Q I S E G M
Honey Bee Apis mellifera XP_392450 898 100991 S721 S C N L K A L S Q S C L M Y M
Nematode Worm Caenorhab. elegans NP_508572 797 90284 Q618 I L K N P T I Q T S Q C I S I
Sea Urchin Strong. purpuratus XP_001202828 913 103393 S734 N C N K S S I S V G A L V Y M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 99.3 96.4 N.A. 95.9 52.8 N.A. 80.1 27.1 21 74.5 N.A. 24.3 30.2 32.8 39.8
Protein Similarity: 100 66 99.5 97.8 N.A. 97.3 66.1 N.A. 85.8 42.8 34.3 82.6 N.A. 41.9 48.7 52 55
P-Site Identity: 100 26.6 86.6 73.3 N.A. 66.6 33.3 N.A. 53.3 0 26.6 53.3 N.A. 6.6 26.6 6.6 20
P-Site Similarity: 100 53.3 93.3 80 N.A. 66.6 46.6 N.A. 66.6 40 40 66.6 N.A. 33.3 66.6 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 0 8 15 15 0 8 0 15 8 0 0 0 0 % A
% Cys: 8 15 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 0 8 8 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 36 0 % F
% Gly: 8 8 8 15 0 0 0 0 0 8 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 29 0 % H
% Ile: 8 0 0 0 0 0 36 0 0 0 8 0 15 0 15 % I
% Lys: 0 0 8 8 8 0 0 0 0 8 8 0 36 0 0 % K
% Leu: 8 15 0 8 8 0 15 0 15 0 0 72 22 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 15 15 8 0 72 % M
% Asn: 15 8 36 8 0 0 0 0 0 0 43 0 0 0 0 % N
% Pro: 0 0 0 8 58 0 8 0 0 15 0 0 0 0 0 % P
% Gln: 8 0 15 8 0 8 0 8 15 8 15 0 0 8 0 % Q
% Arg: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 36 36 15 0 8 8 0 79 0 29 0 8 0 8 0 % S
% Thr: 0 0 0 0 0 65 0 8 8 15 0 0 0 0 0 % T
% Val: 0 0 0 22 0 0 43 0 8 8 0 0 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 58 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _