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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDR2 All Species: 27.27
Human Site: S841 Identified Species: 46.15
UniProt: Q16832 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16832 NP_001014796.1 855 96736 S841 R D T K N R P S F Q E I H L L
Chimpanzee Pan troglodytes Q7YR43 909 100624 P893 R E S E Q R P P F S Q L H R F
Rhesus Macaque Macaca mulatta XP_001118206 855 96702 S841 R D T K N R P S F Q E I H L L
Dog Lupus familis XP_536144 849 95798 S835 R D T K H R P S F Q E I H L L
Cat Felis silvestris
Mouse Mus musculus Q62371 854 96464 S840 R E T K H R P S F Q E I H L L
Rat Rattus norvegicus Q63474 910 101146 P894 R E P E Q R P P F S Q L H R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515915 914 101965 S899 R E T K N R P S F Q E I H L L
Chicken Gallus gallus Q91987 818 91718 L803 I K E I H S L L Q N L A K A S
Frog Xenopus laevis O73798 1358 153845 I1262 F L E I I S S I K D E L D P G
Zebra Danio Brachydanio rerio XP_684261 892 101731 S879 R N T K E R P S F Q E I H H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24488 685 78124 F678 K T W H E G H F K A S N P E M
Honey Bee Apis mellifera XP_392450 898 100991 T879 R D E T S R P T F K D I Y T F
Nematode Worm Caenorhab. elegans NP_508572 797 90284 P776 N Y E S S R R P S F E N V H L
Sea Urchin Strong. purpuratus XP_001202828 913 103393 T892 S E P G Q R P T F D F L H T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.8 99.3 96.4 N.A. 95.9 52.8 N.A. 80.1 27.1 21 74.5 N.A. 24.3 30.2 32.8 39.8
Protein Similarity: 100 66 99.5 97.8 N.A. 97.3 66.1 N.A. 85.8 42.8 34.3 82.6 N.A. 41.9 48.7 52 55
P-Site Identity: 100 33.3 100 93.3 N.A. 86.6 33.3 N.A. 93.3 0 6.6 73.3 N.A. 0 40 20 26.6
P-Site Similarity: 100 66.6 100 100 N.A. 100 60 N.A. 100 6.6 13.3 80 N.A. 13.3 73.3 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 0 0 0 0 0 15 8 0 8 0 0 % D
% Glu: 0 36 29 15 15 0 0 0 0 0 58 0 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 8 72 8 8 0 0 0 29 % F
% Gly: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 8 22 0 8 0 0 0 0 0 65 15 0 % H
% Ile: 8 0 0 15 8 0 0 8 0 0 0 50 0 0 0 % I
% Lys: 8 8 0 43 0 0 0 0 15 8 0 0 8 0 0 % K
% Leu: 0 8 0 0 0 0 8 8 0 0 8 29 0 36 43 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 8 0 0 22 0 0 0 0 8 0 15 0 0 0 % N
% Pro: 0 0 15 0 0 0 72 22 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 22 0 0 0 8 43 15 0 0 0 0 % Q
% Arg: 65 0 0 0 0 79 8 0 0 0 0 0 0 15 0 % R
% Ser: 8 0 8 8 15 15 8 43 8 15 8 0 0 0 8 % S
% Thr: 0 8 43 8 0 0 0 15 0 0 0 0 0 15 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _