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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDR2
All Species:
25.76
Human Site:
T442
Identified Species:
43.59
UniProt:
Q16832
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16832
NP_001014796.1
855
96736
T442
R
M
L
D
D
E
M
T
V
S
L
S
L
P
S
Chimpanzee
Pan troglodytes
Q7YR43
909
100624
T456
R
V
L
E
E
E
L
T
V
H
L
S
V
P
G
Rhesus Macaque
Macaca mulatta
XP_001118206
855
96702
T442
R
M
L
D
D
E
M
T
V
S
L
S
L
P
S
Dog
Lupus familis
XP_536144
849
95798
T436
R
M
L
D
D
E
M
T
V
S
L
S
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62371
854
96464
T442
R
M
L
D
D
E
M
T
V
S
L
S
L
P
S
Rat
Rattus norvegicus
Q63474
910
101146
T457
R
V
L
E
E
E
L
T
V
H
L
S
V
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515915
914
101965
V491
M
L
D
D
E
M
T
V
S
L
S
L
P
S
E
Chicken
Gallus gallus
Q91987
818
91718
Y394
P
I
V
D
P
D
V
Y
E
Y
E
T
T
P
N
Frog
Xenopus laevis
O73798
1358
153845
V739
R
R
R
D
V
L
A
V
G
N
S
T
V
T
S
Zebra Danio
Brachydanio rerio
XP_684261
892
101731
S477
L
D
D
E
L
T
A
S
L
S
I
Q
S
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24488
685
78124
A317
C
A
D
K
I
W
I
A
I
V
G
T
T
A
A
Honey Bee
Apis mellifera
XP_392450
898
100991
H451
M
P
E
D
G
S
M
H
E
S
L
T
M
E
Q
Nematode Worm
Caenorhab. elegans
NP_508572
797
90284
E410
T
V
L
Y
R
K
R
E
Y
R
V
K
A
S
S
Sea Urchin
Strong. purpuratus
XP_001202828
913
103393
F475
H
R
L
P
T
L
A
F
E
A
N
C
N
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
99.3
96.4
N.A.
95.9
52.8
N.A.
80.1
27.1
21
74.5
N.A.
24.3
30.2
32.8
39.8
Protein Similarity:
100
66
99.5
97.8
N.A.
97.3
66.1
N.A.
85.8
42.8
34.3
82.6
N.A.
41.9
48.7
52
55
P-Site Identity:
100
53.3
100
100
N.A.
100
53.3
N.A.
6.6
13.3
20
6.6
N.A.
0
26.6
13.3
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
86.6
N.A.
20
53.3
40
40
N.A.
26.6
40
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
22
8
0
8
0
0
8
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
22
58
29
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
22
22
43
0
8
22
0
8
0
0
15
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
8
0
0
8
22
% G
% His:
8
0
0
0
0
0
0
8
0
15
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
8
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
58
0
8
15
15
0
8
8
50
8
29
0
0
% L
% Met:
15
29
0
0
0
8
36
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
8
% N
% Pro:
8
8
0
8
8
0
0
0
0
0
0
0
8
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
50
15
8
0
8
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
8
43
15
43
8
15
43
% S
% Thr:
8
0
0
0
8
8
8
43
0
0
0
29
15
8
8
% T
% Val:
0
22
8
0
8
0
8
15
43
8
8
0
22
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _