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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HADH
All Species:
35.15
Human Site:
S73
Identified Species:
70.3
UniProt:
Q16836
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16836
NP_005318.2
314
34278
S73
S
K
K
G
I
E
E
S
L
R
K
V
A
K
K
Chimpanzee
Pan troglodytes
XP_517385
390
42181
S132
S
K
K
G
I
E
E
S
L
R
K
V
A
K
K
Rhesus Macaque
Macaca mulatta
XP_001084834
496
54433
S238
S
K
K
G
I
E
E
S
L
R
K
V
A
K
K
Dog
Lupus familis
XP_535685
312
34317
S71
S
K
K
G
I
E
E
S
L
R
R
V
A
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61425
314
34445
S73
S
K
K
G
I
E
E
S
L
K
R
M
A
K
K
Rat
Rattus norvegicus
Q9WVK7
314
34429
S73
S
K
K
G
I
E
E
S
L
K
R
M
A
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511764
360
39012
S119
S
R
R
G
I
E
D
S
L
K
R
V
A
K
K
Chicken
Gallus gallus
XP_418403
315
34403
S74
S
T
K
G
I
E
E
S
L
K
R
V
T
K
K
Frog
Xenopus laevis
NP_001080900
313
34295
S72
S
R
K
S
I
E
D
S
L
K
R
V
T
K
K
Zebra Danio
Brachydanio rerio
NP_001003515
309
33318
K75
S
L
K
R
V
A
K
K
K
F
A
E
K
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41938
309
33362
K75
S
L
K
R
V
A
K
K
K
H
A
D
D
A
A
Sea Urchin
Strong. purpuratus
XP_787188
292
31577
V70
P
A
G
G
T
E
F
V
N
S
I
L
G
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
61.4
92.3
N.A.
90.1
90.4
N.A.
70
77.7
79.3
76.1
N.A.
N.A.
N.A.
53.8
58.6
Protein Similarity:
100
80
62.7
97.7
N.A.
97.1
97.1
N.A.
79.1
90.1
87.9
84.7
N.A.
N.A.
N.A.
67.1
74.5
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
66.6
73.3
60
13.3
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
86.6
33.3
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
17
0
0
0
0
17
0
59
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
0
0
0
9
9
0
0
% D
% Glu:
0
0
0
0
0
84
59
0
0
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
9
75
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
75
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
50
84
0
0
0
17
17
17
42
25
0
9
75
75
% K
% Leu:
0
17
0
0
0
0
0
0
75
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
9
17
0
0
0
0
0
34
50
0
0
0
0
% R
% Ser:
92
0
0
9
0
0
0
75
0
9
0
0
0
9
0
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
0
0
17
0
0
% T
% Val:
0
0
0
0
17
0
0
9
0
0
0
59
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _