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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP51A1
All Species:
23.03
Human Site:
S60
Identified Species:
38.97
UniProt:
Q16850
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16850
NP_000777.1
503
56806
S60
Q
L
P
A
G
V
K
S
P
P
Y
I
F
S
P
Chimpanzee
Pan troglodytes
XP_519193
509
57278
S66
Q
L
P
A
G
V
K
S
P
P
Y
I
F
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532457
503
56745
S60
P
L
P
A
G
A
K
S
P
P
Y
I
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0C4
503
56757
S60
Q
L
P
A
G
A
K
S
P
P
H
I
Y
S
P
Rat
Rattus norvegicus
Q64654
503
56688
S60
Q
L
P
A
G
A
K
S
P
P
Y
I
Y
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517490
563
61243
I88
R
P
P
R
D
F
P
I
G
V
D
G
H
R
R
Chicken
Gallus gallus
Q9PUB4
492
55246
F53
P
G
T
M
G
L
P
F
F
G
E
T
L
Q
M
Frog
Xenopus laevis
NP_001091285
501
56963
Y58
E
D
P
G
N
V
K
Y
P
P
Y
I
S
S
H
Zebra Danio
Brachydanio rerio
NP_001001730
499
56983
Y52
H
S
S
E
H
T
K
Y
P
P
H
I
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33269
512
58673
T67
K
I
F
E
F
M
E
T
Y
S
K
D
Q
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001001906
496
56226
P52
Q
N
K
D
V
K
L
P
P
R
L
P
T
G
I
Poplar Tree
Populus trichocarpa
XP_002299356
488
55530
F54
L
I
G
G
L
I
R
F
L
K
G
P
I
V
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTM7
502
57706
R52
Q
V
G
E
L
P
H
R
S
F
Q
R
L
A
E
Baker's Yeast
Sacchar. cerevisiae
P10614
530
60702
R55
L
Y
S
L
R
K
D
R
P
P
L
V
F
Y
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
96.6
N.A.
91.2
93.4
N.A.
58
23.6
80.3
75.9
N.A.
20.7
N.A.
N.A.
66.8
Protein Similarity:
100
98.6
N.A.
98.6
N.A.
96.6
97.4
N.A.
65.5
42.5
89.4
86.6
N.A.
40.6
N.A.
N.A.
81.3
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
86.6
N.A.
6.6
6.6
53.3
33.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
13.3
13.3
60
40
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
37.9
N.A.
N.A.
20.4
35
N.A.
Protein Similarity:
56.4
N.A.
N.A.
37.3
54.9
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
0
22
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
8
0
0
0
8
8
0
0
0
% D
% Glu:
8
0
0
22
0
0
8
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
8
8
0
15
8
8
0
0
29
0
0
% F
% Gly:
0
8
15
15
43
0
0
0
8
8
8
8
0
8
0
% G
% His:
8
0
0
0
8
0
8
0
0
0
15
0
8
0
8
% H
% Ile:
0
15
0
0
0
8
0
8
0
0
0
50
8
0
8
% I
% Lys:
8
0
8
0
0
15
50
0
0
8
8
0
0
0
0
% K
% Leu:
15
36
0
8
15
8
8
0
8
0
15
0
15
0
8
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
8
50
0
0
8
15
8
65
58
0
15
8
0
36
% P
% Gln:
43
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% Q
% Arg:
8
0
0
8
8
0
8
15
0
8
0
8
0
8
8
% R
% Ser:
0
8
15
0
0
0
0
36
8
8
0
0
8
50
8
% S
% Thr:
0
0
8
0
0
8
0
8
0
0
0
8
8
0
0
% T
% Val:
0
8
0
0
8
22
0
0
0
8
0
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
0
15
8
0
36
0
15
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _