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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGUOK
All Species:
17.88
Human Site:
S257
Identified Species:
39.33
UniProt:
Q16854
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16854
NP_550438.1
277
32056
S257
L
D
V
N
D
D
F
S
E
E
V
T
K
Q
E
Chimpanzee
Pan troglodytes
XP_001153473
277
32123
S257
L
D
V
N
D
D
F
S
E
E
V
T
K
Q
E
Rhesus Macaque
Macaca mulatta
XP_001107072
277
32120
S257
L
D
V
N
D
D
F
S
E
E
V
T
K
Q
E
Dog
Lupus familis
XP_533001
277
32031
S257
L
D
V
N
D
D
F
S
E
E
V
T
K
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QX60
277
32204
S257
L
D
V
T
E
D
F
S
E
N
A
A
R
Q
E
Rat
Rattus norvegicus
P48769
260
30388
D241
L
T
L
D
V
N
L
D
F
K
D
K
E
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513929
188
22099
D169
E
E
K
D
V
G
L
D
Y
L
E
K
L
H
A
Chicken
Gallus gallus
NP_001072968
265
31222
K246
L
D
V
N
E
D
F
K
N
D
K
I
K
Q
E
Frog
Xenopus laevis
NP_001085591
265
31380
E245
L
N
V
E
E
D
F
E
N
N
S
A
A
G
D
Zebra Danio
Brachydanio rerio
NP_001093561
269
31271
E249
L
D
A
E
V
A
F
E
Q
N
P
E
V
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZT6
250
29070
S231
S
I
F
D
A
I
S
S
N
Q
Q
P
S
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96
84.1
N.A.
75
46.9
N.A.
44.7
50.9
48.7
50.1
N.A.
30.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
98.5
91.3
N.A.
85.1
64.9
N.A.
54.1
68.2
69.3
66.7
N.A.
50.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
60
6.6
N.A.
0
60
26.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
73.3
46.6
N.A.
13.3
73.3
46.6
40
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
0
0
0
0
10
19
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
64
0
28
37
64
0
19
0
10
10
0
0
0
19
% D
% Glu:
10
10
0
19
28
0
0
19
46
37
10
10
10
10
55
% E
% Phe:
0
0
10
0
0
0
73
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
10
10
19
46
0
0
% K
% Leu:
82
0
10
0
0
0
19
0
0
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
46
0
10
0
0
28
28
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
10
0
0
64
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
10
55
0
0
10
0
10
0
10
% S
% Thr:
0
10
0
10
0
0
0
0
0
0
0
37
0
0
0
% T
% Val:
0
0
64
0
28
0
0
0
0
0
37
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _