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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGUOK All Species: 13.33
Human Site: S91 Identified Species: 29.33
UniProt: Q16854 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16854 NP_550438.1 277 32056 S91 Q K A C T A Q S L G N L L D M
Chimpanzee Pan troglodytes XP_001153473 277 32123 S91 Q K A C T A Q S L G N L L D M
Rhesus Macaque Macaca mulatta XP_001107072 277 32120 S91 Q K A C T A Q S L G N L L D M
Dog Lupus familis XP_533001 277 32031 S91 Q K A F T A Q S L G N L L D M
Cat Felis silvestris
Mouse Mus musculus Q9QX60 277 32204 R91 Q K D G T S K R L G N L L E M
Rat Rattus norvegicus P48769 260 30388 F94 E K P E R W S F I F Q S Y A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513929 188 22099 E22 P D W H V A A E P V E T W Q K
Chicken Gallus gallus NP_001072968 265 31222 K91 L L Q M L Y D K P T R W A Y T
Frog Xenopus laevis NP_001085591 265 31380 D90 L L Q L M Y D D P K R W S Y T
Zebra Danio Brachydanio rerio NP_001093561 269 31271 R92 N L L E M M Y R D P K R W S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XZT6 250 29070 V84 A M P F Q S Y V T L T M L Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96 84.1 N.A. 75 46.9 N.A. 44.7 50.9 48.7 50.1 N.A. 30.6 N.A. N.A. N.A.
Protein Similarity: 100 99.2 98.5 91.3 N.A. 85.1 64.9 N.A. 54.1 68.2 69.3 66.7 N.A. 50.1 N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 60 6.6 N.A. 6.6 0 0 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 20 N.A. 6.6 0 0 0 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 37 0 0 46 10 0 0 0 0 0 10 10 0 % A
% Cys: 0 0 0 28 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 10 0 0 0 19 10 10 0 0 0 0 37 0 % D
% Glu: 10 0 0 19 0 0 0 10 0 0 10 0 0 10 0 % E
% Phe: 0 0 0 19 0 0 0 10 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 46 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 55 0 0 0 0 10 10 0 10 10 0 0 0 10 % K
% Leu: 19 28 10 10 10 0 0 0 46 10 0 46 55 0 0 % L
% Met: 0 10 0 10 19 10 0 0 0 0 0 10 0 0 46 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % N
% Pro: 10 0 19 0 0 0 0 0 28 10 0 0 0 0 0 % P
% Gln: 46 0 19 0 10 0 37 0 0 0 10 0 0 19 0 % Q
% Arg: 0 0 0 0 10 0 0 19 0 0 19 10 0 0 0 % R
% Ser: 0 0 0 0 0 19 10 37 0 0 0 10 10 10 10 % S
% Thr: 0 0 0 0 46 0 0 0 10 10 10 10 0 0 19 % T
% Val: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 10 0 0 0 0 0 19 19 0 0 % W
% Tyr: 0 0 0 0 0 19 19 0 0 0 0 0 10 19 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _