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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LTC4S All Species: 21.21
Human Site: S111 Identified Species: 46.67
UniProt: Q16873 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16873 NP_665874.1 150 16567 S111 R L A P L Y A S A R A L W L L
Chimpanzee Pan troglodytes XP_001153488 150 16532 S111 R L A P L Y A S A R A L W L L
Rhesus Macaque Macaca mulatta P30354 153 17257 G115 S T P G Y I F G K R I I L F L
Dog Lupus familis XP_849032 166 17982 W132 Y A S A R A L W L L M A L A A
Cat Felis silvestris
Mouse Mus musculus Q60860 150 16796 S111 R L T P L Y A S A R A L W L L
Rat Rattus norvegicus Q925U2 150 16817 S111 R L D P L Y A S A R A L W L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512496 188 21604 T111 R I K G F R L T V G I L T L L
Chicken Gallus gallus XP_414609 145 16346 S111 R L T P I Y F S T G V L W V L
Frog Xenopus laevis NP_001088328 140 15585 N111 R L G P M Y L N A A I L W L L
Zebra Danio Brachydanio rerio XP_695668 153 17256 S111 R L E P L Y F S A K M Q W V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788981 153 17069 C115 R L F G F G V C V N A L K L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 32 79.5 N.A. 88 86 N.A. 33.5 58.6 56.6 54.9 N.A. N.A. N.A. N.A. 38.5
Protein Similarity: 100 99.3 47 80.7 N.A. 91.3 90 N.A. 48.9 72.6 75.3 70.5 N.A. N.A. N.A. N.A. 52.2
P-Site Identity: 100 100 13.3 0 N.A. 93.3 93.3 N.A. 26.6 53.3 60 60 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 20 6.6 N.A. 93.3 93.3 N.A. 40 66.6 73.3 73.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 10 0 10 37 0 55 10 46 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 19 0 28 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 10 28 0 10 0 10 0 19 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 10 0 0 0 0 28 10 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 10 10 0 0 10 0 0 % K
% Leu: 0 73 0 0 46 0 28 0 10 10 0 73 19 64 91 % L
% Met: 0 0 0 0 10 0 0 0 0 0 19 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 64 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 82 0 0 0 10 10 0 0 0 46 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 0 0 55 0 0 0 0 0 0 0 % S
% Thr: 0 10 19 0 0 0 0 10 10 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 10 0 19 0 10 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 64 0 0 % W
% Tyr: 10 0 0 0 10 64 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _