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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LTC4S All Species: 27.88
Human Site: S36 Identified Species: 61.33
UniProt: Q16873 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16873 NP_665874.1 150 16567 S36 A R R A F R V S P P L T T G P
Chimpanzee Pan troglodytes XP_001153488 150 16532 S36 A R R A F R V S P P L T T G P
Rhesus Macaque Macaca mulatta P30354 153 17257 R40 E S R T Q N G R S F Q R T G T
Dog Lupus familis XP_849032 166 17982 S57 A R R A F R V S P P L T T G P
Cat Felis silvestris
Mouse Mus musculus Q60860 150 16796 S36 A R R A F H V S P P L T S G P
Rat Rattus norvegicus Q925U2 150 16817 S36 A R R T F H V S P P L T S G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512496 188 21604 M36 A R F K Y K I M P P A V S G S
Chicken Gallus gallus XP_414609 145 16346 S36 A R R K F G I S P P N I S G P
Frog Xenopus laevis NP_001088328 140 15585 S36 A R R K Y S V S P P S T S G P
Zebra Danio Brachydanio rerio XP_695668 153 17256 S36 A R R K Y A V S P P A T S G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788981 153 17069 P40 A R R K F D V P Y P A I T G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 32 79.5 N.A. 88 86 N.A. 33.5 58.6 56.6 54.9 N.A. N.A. N.A. N.A. 38.5
Protein Similarity: 100 99.3 47 80.7 N.A. 91.3 90 N.A. 48.9 72.6 75.3 70.5 N.A. N.A. N.A. N.A. 52.2
P-Site Identity: 100 100 20 100 N.A. 86.6 80 N.A. 33.3 60 66.6 66.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 20 100 N.A. 93.3 86.6 N.A. 60 73.3 80 80 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 91 0 0 37 0 10 0 0 0 0 28 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 64 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 0 46 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 82 91 0 0 0 0 73 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 91 91 0 0 28 0 10 0 0 0 10 0 0 0 % R
% Ser: 0 10 0 0 0 10 0 73 10 0 10 0 55 0 10 % S
% Thr: 0 0 0 19 0 0 0 0 0 0 0 64 46 0 10 % T
% Val: 0 0 0 0 0 0 73 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 28 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _