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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LTC4S All Species: 35.76
Human Site: T41 Identified Species: 78.67
UniProt: Q16873 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16873 NP_665874.1 150 16567 T41 R V S P P L T T G P P E F E R
Chimpanzee Pan troglodytes XP_001153488 150 16532 T41 R V S P P L T T G P P E F E R
Rhesus Macaque Macaca mulatta P30354 153 17257 T45 N G R S F Q R T G T L A F E R
Dog Lupus familis XP_849032 166 17982 T62 R V S P P L T T G P P E F E R
Cat Felis silvestris
Mouse Mus musculus Q60860 150 16796 S41 H V S P P L T S G P P E F E R
Rat Rattus norvegicus Q925U2 150 16817 S41 H V S P P L T S G P P E F E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512496 188 21604 S41 K I M P P A V S G S P E F E R
Chicken Gallus gallus XP_414609 145 16346 S41 G I S P P N I S G P P E F E R
Frog Xenopus laevis NP_001088328 140 15585 S41 S V S P P S T S G P P E F D R
Zebra Danio Brachydanio rerio XP_695668 153 17256 S41 A V S P P A T S G P P E F E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788981 153 17069 T45 D V P Y P A I T G D E R F M R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 32 79.5 N.A. 88 86 N.A. 33.5 58.6 56.6 54.9 N.A. N.A. N.A. N.A. 38.5
Protein Similarity: 100 99.3 47 80.7 N.A. 91.3 90 N.A. 48.9 72.6 75.3 70.5 N.A. N.A. N.A. N.A. 52.2
P-Site Identity: 100 100 33.3 100 N.A. 86.6 86.6 N.A. 53.3 66.6 73.3 80 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 33.3 100 N.A. 93.3 93.3 N.A. 73.3 80 86.6 86.6 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 28 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 10 82 0 82 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 100 0 0 % F
% Gly: 10 10 0 0 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 19 0 0 0 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 46 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 82 91 0 0 0 0 73 82 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 28 0 10 0 0 0 10 0 0 0 0 10 0 0 100 % R
% Ser: 10 0 73 10 0 10 0 55 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 64 46 0 10 0 0 0 0 0 % T
% Val: 0 73 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _