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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LTC4S All Species: 14.85
Human Site: Y50 Identified Species: 32.67
UniProt: Q16873 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16873 NP_665874.1 150 16567 Y50 P P E F E R V Y R A Q V N C S
Chimpanzee Pan troglodytes XP_001153488 150 16532 Y50 P P E F E R V Y R A Q V N C S
Rhesus Macaque Macaca mulatta P30354 153 17257 Y54 T L A F E R V Y T A N Q N C V
Dog Lupus familis XP_849032 166 17982 Y71 P P E F E R V Y R A Q V N C S
Cat Felis silvestris
Mouse Mus musculus Q60860 150 16796 F50 P P E F E R V F R A Q V N C S
Rat Rattus norvegicus Q925U2 150 16817 F50 P P E F E R V F R A Q V N C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512496 188 21604 Y50 S P E F E R I Y R A H Q N C V
Chicken Gallus gallus XP_414609 145 16346 F50 P P E F E R I F R A Q V N S S
Frog Xenopus laevis NP_001088328 140 15585 F50 P P E F D R I F R A Q V N C T
Zebra Danio Brachydanio rerio XP_695668 153 17256 F50 P P E F E R I F R A Q A N C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788981 153 17069 F54 D E R F M R Y F R A Q Q N T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 32 79.5 N.A. 88 86 N.A. 33.5 58.6 56.6 54.9 N.A. N.A. N.A. N.A. 38.5
Protein Similarity: 100 99.3 47 80.7 N.A. 91.3 90 N.A. 48.9 72.6 75.3 70.5 N.A. N.A. N.A. N.A. 52.2
P-Site Identity: 100 100 53.3 100 N.A. 93.3 93.3 N.A. 66.6 80 73.3 80 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 53.3 100 N.A. 100 100 N.A. 73.3 93.3 100 93.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 100 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 % C
% Asp: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 82 0 82 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 100 0 0 0 55 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 37 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 100 0 0 % N
% Pro: 73 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 82 28 0 0 0 % Q
% Arg: 0 0 10 0 0 100 0 0 91 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 64 % S
% Thr: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 10 % T
% Val: 0 0 0 0 0 0 55 0 0 0 0 64 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 46 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _