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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
20.91
Human Site:
S423
Identified Species:
32.86
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
S423
R
L
R
V
V
A
Q
S
T
N
S
E
E
I
I
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
I280
S
T
N
S
E
E
I
I
E
G
E
Y
N
T
V
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
E304
E
D
C
T
T
G
K
E
D
T
G
T
F
D
T
Dog
Lupus familis
XP_850181
509
55065
K290
W
E
N
L
T
S
G
K
E
D
V
G
T
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
S387
R
L
R
V
T
A
Q
S
T
N
S
E
E
T
I
Rat
Rattus norvegicus
O89049
498
54218
T279
K
S
T
N
S
E
E
T
I
E
D
E
F
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
S397
K
L
K
V
V
A
Q
S
T
D
G
Q
E
T
I
Chicken
Gallus gallus
NP_001116249
606
66439
S380
R
L
K
V
T
A
K
S
T
E
G
P
E
F
F
Frog
Xenopus laevis
NP_001087660
596
65709
S372
R
I
K
V
T
A
K
S
T
Q
G
D
Q
I
I
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
S376
R
I
K
V
T
A
K
S
T
E
S
E
E
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Y370
D
G
K
L
L
V
K
Y
K
N
V
E
T
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
E439
V
F
W
P
K
K
N
E
E
T
G
E
M
Q
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
G346
T
S
K
G
T
V
E
G
F
S
H
V
M
F
A
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
V264
K
L
S
K
I
V
K
V
E
K
N
V
E
T
D
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
A249
T
S
V
Q
K
D
A
A
G
K
L
A
I
N
F
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
0
0
0
N.A.
86.6
6.6
N.A.
60
46.6
46.6
53.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
6.6
20
N.A.
86.6
26.6
N.A.
86.6
60
80
80
N.A.
40
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
40
7
7
0
0
0
7
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
7
0
0
7
14
7
7
0
7
14
% D
% Glu:
7
7
0
0
7
14
14
14
27
20
7
40
40
0
14
% E
% Phe:
0
7
0
0
0
0
0
0
7
0
0
0
14
20
20
% F
% Gly:
0
7
0
7
0
7
7
7
7
7
34
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
14
0
0
7
0
7
7
7
0
0
0
7
14
27
% I
% Lys:
20
0
40
7
14
7
40
7
7
14
0
0
0
0
0
% K
% Leu:
0
34
0
14
7
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
14
7
0
0
7
0
0
20
7
0
7
14
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
20
0
0
7
0
7
7
7
0
% Q
% Arg:
34
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
20
7
7
7
7
0
40
0
7
20
0
0
0
0
% S
% Thr:
14
7
7
7
47
0
0
7
40
14
0
7
14
27
14
% T
% Val:
7
0
7
40
14
20
0
7
0
0
14
14
0
7
7
% V
% Trp:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _