KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
6.36
Human Site:
S617
Identified Species:
10
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
S617
L
T
K
K
Q
L
D
S
T
I
G
I
H
P
V
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
T468
T
K
K
Q
L
D
S
T
I
G
I
H
P
V
C
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
R492
A
S
Y
A
Q
V
M
R
T
V
G
I
H
P
T
Dog
Lupus familis
XP_850181
509
55065
M478
G
A
S
Y
A
Q
V
M
R
T
V
G
I
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
S581
L
T
K
Q
Q
L
D
S
T
I
G
I
H
P
V
Rat
Rattus norvegicus
O89049
498
54218
T467
T
K
Q
Q
L
D
S
T
I
G
I
H
P
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
D590
G
L
T
K
E
Q
L
D
S
T
I
G
I
H
P
Chicken
Gallus gallus
NP_001116249
606
66439
E574
L
T
K
E
L
L
D
E
T
I
G
I
H
P
T
Frog
Xenopus laevis
NP_001087660
596
65709
D565
G
L
T
K
E
K
L
D
E
T
I
G
I
H
P
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
N570
I
T
K
D
Q
L
D
N
T
I
G
I
H
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
N564
L
T
I
N
T
L
I
N
T
V
G
I
H
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
R634
A
K
K
A
D
F
D
R
L
I
G
I
H
P
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
E534
G
V
H
P
T
A
A
E
E
F
V
T
M
R
A
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
F452
S
A
E
I
L
Q
G
F
G
V
A
I
K
M
G
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
F437
S
G
E
I
L
Q
G
F
G
V
A
V
N
M
G
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
6.6
40
0
N.A.
93.3
0
N.A.
6.6
73.3
6.6
73.3
N.A.
53.3
N.A.
46.6
N.A.
P-Site Similarity:
100
20
60
0
N.A.
100
20
N.A.
20
80
13.3
86.6
N.A.
66.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
14
7
7
7
0
0
0
14
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% C
% Asp:
0
0
0
7
7
14
34
14
0
0
0
0
0
0
0
% D
% Glu:
0
0
14
7
14
0
0
14
14
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
14
0
7
0
0
0
0
0
% F
% Gly:
27
7
0
0
0
0
14
0
14
14
47
20
0
0
14
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
14
47
20
0
% H
% Ile:
7
0
7
14
0
0
7
0
14
34
27
54
20
0
0
% I
% Lys:
0
20
40
20
0
7
0
0
0
0
0
0
7
0
0
% K
% Leu:
27
14
0
0
34
34
14
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
0
7
14
0
% M
% Asn:
0
0
0
7
0
0
0
14
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
14
47
20
% P
% Gln:
0
0
7
20
27
27
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
14
7
0
0
0
0
7
0
% R
% Ser:
14
7
7
0
0
0
14
14
7
0
0
0
0
0
0
% S
% Thr:
14
34
14
0
14
0
0
14
40
20
0
7
0
0
34
% T
% Val:
0
7
0
0
0
7
7
0
0
27
14
7
0
14
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _