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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
17.88
Human Site:
T413
Identified Species:
28.1
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
T413
V
E
Q
I
E
A
G
T
P
G
R
L
R
V
V
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
V270
T
P
G
R
L
R
V
V
A
Q
S
T
N
S
E
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
V294
L
P
D
G
H
L
Q
V
T
W
E
D
C
T
T
Dog
Lupus familis
XP_850181
509
55065
Q280
R
L
P
D
G
Q
L
Q
V
T
W
E
N
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
T377
I
E
Q
I
E
A
G
T
P
G
R
L
R
V
T
Rat
Rattus norvegicus
O89049
498
54218
V269
G
T
P
G
R
L
K
V
T
A
K
S
T
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
M387
I
E
Q
I
E
E
G
M
P
G
K
L
K
V
V
Chicken
Gallus gallus
NP_001116249
606
66439
T370
V
E
R
L
E
D
G
T
P
G
R
L
K
V
T
Frog
Xenopus laevis
NP_001087660
596
65709
T362
V
E
L
L
E
E
G
T
P
G
R
I
K
V
T
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
T366
I
E
Q
L
E
A
G
T
P
G
R
I
K
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
K360
T
V
P
L
S
V
E
K
Q
D
D
G
K
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
K429
K
T
D
E
K
A
G
K
Y
R
V
F
W
P
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
S336
K
A
G
D
G
S
F
S
L
K
T
S
K
G
T
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
N254
H
Y
V
K
E
G
I
N
V
H
K
L
S
K
I
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
S239
G
V
K
V
H
K
K
S
Q
L
T
S
V
Q
K
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
0
0
0
N.A.
86.6
0
N.A.
66.6
66.6
60
66.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
0
6.6
6.6
N.A.
93.3
6.6
N.A.
86.6
86.6
80
93.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
27
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
14
14
0
7
0
0
0
7
7
7
0
0
0
% D
% Glu:
0
40
0
7
47
14
7
0
0
0
7
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% F
% Gly:
14
0
14
14
14
7
47
0
0
40
0
7
0
7
0
% G
% His:
7
0
0
0
14
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
20
0
0
20
0
0
7
0
0
0
0
14
0
0
7
% I
% Lys:
14
0
7
7
7
7
14
14
0
7
20
0
40
7
14
% K
% Leu:
7
7
7
27
7
14
7
0
7
7
0
34
0
14
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
14
7
0
% N
% Pro:
0
14
20
0
0
0
0
0
40
0
0
0
0
7
0
% P
% Gln:
0
0
27
0
0
7
7
7
14
7
0
0
0
7
0
% Q
% Arg:
7
0
7
7
7
7
0
0
0
7
34
0
14
0
0
% R
% Ser:
0
0
0
0
7
7
0
14
0
0
7
20
7
7
7
% S
% Thr:
14
14
0
0
0
0
0
34
14
7
14
7
7
7
47
% T
% Val:
20
14
7
7
0
7
7
20
14
0
7
0
7
40
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
7
0
7
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _