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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
21.52
Human Site:
T447
Identified Species:
33.81
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
T447
A
I
G
R
D
A
C
T
R
K
I
G
L
E
T
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
T304
T
R
K
I
G
L
E
T
V
G
V
K
I
N
E
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
E328
D
T
R
S
L
N
L
E
K
A
G
V
D
T
S
Dog
Lupus familis
XP_850181
509
55065
L314
P
E
T
K
S
L
N
L
E
K
A
G
V
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
T411
A
V
G
R
D
S
C
T
R
T
I
G
L
E
T
Rat
Rattus norvegicus
O89049
498
54218
E303
C
T
R
T
I
G
L
E
T
V
G
V
K
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
T421
A
V
G
R
D
S
C
T
R
K
I
G
L
E
N
Chicken
Gallus gallus
NP_001116249
606
66439
T404
A
I
G
R
D
A
C
T
R
N
I
G
L
Q
T
Frog
Xenopus laevis
NP_001087660
596
65709
T396
A
V
G
R
D
A
C
T
R
N
I
G
L
E
K
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
T400
A
V
G
R
D
A
C
T
G
K
I
G
L
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
G394
L
W
A
I
G
R
K
G
L
V
D
D
L
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
V463
M
A
I
G
R
E
A
V
T
D
D
V
G
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
V370
L
G
L
E
N
V
G
V
K
M
A
K
N
G
A
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
E288
K
S
I
D
D
V
D
E
L
I
W
T
I
G
R
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
W273
S
D
V
D
H
L
I
W
A
V
G
R
T
P
A
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
6.6
0
20
N.A.
80
0
N.A.
80
86.6
80
73.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
20
13.3
33.3
N.A.
93.3
0
N.A.
93.3
93.3
86.6
86.6
N.A.
6.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
7
7
0
0
27
7
0
7
7
14
0
0
0
14
% A
% Cys:
7
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
14
47
0
7
0
0
7
14
7
7
7
0
% D
% Glu:
0
7
0
7
0
7
7
20
7
0
0
0
0
27
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
40
7
14
7
7
7
7
7
20
47
7
14
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
14
14
7
0
7
0
0
7
40
0
14
7
0
% I
% Lys:
7
0
7
7
0
0
7
0
14
27
0
14
7
0
14
% K
% Leu:
14
0
7
0
7
20
14
7
14
0
0
0
47
7
7
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
7
0
0
14
0
0
7
20
14
% N
% Pro:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
7
14
40
7
7
0
0
34
0
0
7
0
0
7
% R
% Ser:
7
7
0
7
7
14
0
0
0
0
0
0
0
0
7
% S
% Thr:
7
14
7
7
0
0
0
47
14
7
0
7
7
7
34
% T
% Val:
0
27
7
0
0
14
0
14
7
20
7
20
7
0
0
% V
% Trp:
0
7
0
0
0
0
0
7
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _