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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
29.7
Human Site:
T522
Identified Species:
46.67
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
T522
C
D
Y
E
N
V
P
T
T
V
F
T
P
L
E
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
E379
T
T
V
F
T
P
L
E
Y
G
A
C
G
L
S
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
L403
P
T
T
V
F
T
P
L
E
Y
G
C
V
G
L
Dog
Lupus familis
XP_850181
509
55065
P389
V
P
T
T
V
F
T
P
L
E
Y
G
C
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
T486
C
D
Y
D
N
V
P
T
T
V
F
T
P
L
E
Rat
Rattus norvegicus
O89049
498
54218
L378
P
T
T
V
F
T
P
L
E
Y
G
C
C
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
T496
C
D
Y
D
N
V
P
T
T
V
F
T
P
L
E
Chicken
Gallus gallus
NP_001116249
606
66439
T479
C
D
Y
I
N
V
P
T
T
V
F
T
P
L
E
Frog
Xenopus laevis
NP_001087660
596
65709
T471
C
D
Y
I
N
V
P
T
T
V
F
T
P
L
E
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
T475
C
D
Y
V
N
V
P
T
T
V
F
T
P
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
T469
M
D
Y
K
D
V
A
T
T
V
F
T
P
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
T538
T
E
Y
D
Q
I
P
T
T
V
F
T
P
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
G445
Q
P
P
I
G
T
V
G
L
T
E
E
Q
A
I
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
R363
L
F
G
P
E
K
F
R
N
D
K
L
D
Y
E
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
L348
G
P
E
E
F
R
T
L
K
L
N
Y
D
N
V
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
93.3
6.6
N.A.
93.3
93.3
93.3
86.6
N.A.
73.3
N.A.
66.6
N.A.
P-Site Similarity:
100
6.6
6.6
13.3
N.A.
100
6.6
N.A.
100
93.3
93.3
93.3
N.A.
86.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
7
0
0
7
0
% A
% Cys:
40
0
0
0
0
0
0
0
0
0
0
20
14
0
0
% C
% Asp:
0
47
0
20
7
0
0
0
0
7
0
0
14
0
0
% D
% Glu:
0
7
7
14
7
0
0
7
14
7
7
7
0
0
60
% E
% Phe:
0
7
0
7
20
7
7
0
0
0
54
0
0
0
0
% F
% Gly:
7
0
7
0
7
0
0
7
0
7
14
7
7
14
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
20
0
7
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
7
0
7
0
0
7
0
7
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
7
20
14
7
0
7
0
54
14
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
0
40
0
0
0
7
0
7
0
0
7
0
% N
% Pro:
14
20
7
7
0
7
60
7
0
0
0
0
54
0
0
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% S
% Thr:
14
20
20
7
7
20
14
54
54
7
0
54
0
0
0
% T
% Val:
7
0
7
20
7
47
7
0
0
54
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
0
0
0
0
0
7
14
7
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _