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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
0
Human Site:
Y140
Identified Species:
0
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
Y140
H
G
P
T
L
K
A
Y
Q
E
G
R
L
Q
K
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
F43
K
K
V
M
V
L
D
F
V
T
P
T
P
L
G
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
V67
Q
L
G
R
K
V
A
V
V
D
Y
V
E
P
S
Dog
Lupus familis
XP_850181
509
55065
A53
A
Q
L
G
K
K
V
A
V
V
D
Y
V
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
A142
G
S
G
G
L
A
A
A
K
E
A
A
K
F
D
Rat
Rattus norvegicus
O89049
498
54218
D42
D
K
K
V
M
V
L
D
F
V
T
P
T
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
P132
M
N
N
A
N
N
I
P
E
S
F
D
Y
D
L
Chicken
Gallus gallus
NP_001116249
606
66439
K136
S
G
G
L
A
C
S
K
E
A
A
T
L
G
K
Frog
Xenopus laevis
NP_001087660
596
65709
A131
L
A
C
S
K
E
A
A
S
F
G
K
K
V
M
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
A135
L
A
C
S
K
E
A
A
T
L
G
K
K
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
K131
S
A
G
L
A
C
A
K
E
A
V
L
N
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
L153
K
G
N
A
V
G
G
L
K
E
L
K
A
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
F109
A
S
R
F
A
T
S
F
G
A
S
A
A
V
C
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
L27
N
T
K
H
Y
D
Y
L
V
I
G
G
G
S
G
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
V12
S
R
E
T
D
F
L
V
I
G
G
G
S
G
G
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
0
6.6
6.6
N.A.
20
0
N.A.
0
20
13.3
13.3
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
13.3
13.3
20
N.A.
26.6
6.6
N.A.
6.6
33.3
33.3
33.3
N.A.
13.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
20
0
14
20
7
40
27
0
20
14
14
14
0
7
% A
% Cys:
0
0
14
0
0
14
0
0
0
0
0
0
0
0
7
% C
% Asp:
7
0
0
0
7
7
7
7
0
7
7
7
0
7
7
% D
% Glu:
0
0
7
0
0
14
0
0
20
20
0
0
7
7
0
% E
% Phe:
0
0
0
7
0
7
0
14
7
7
7
0
0
7
0
% F
% Gly:
7
20
27
14
0
7
7
0
7
7
34
14
7
20
20
% G
% His:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
7
7
0
0
0
0
0
% I
% Lys:
14
14
14
0
27
14
0
14
14
0
0
20
20
0
20
% K
% Leu:
14
7
7
14
14
7
14
14
0
7
7
7
14
14
14
% L
% Met:
7
0
0
7
7
0
0
0
0
0
0
0
0
0
14
% M
% Asn:
7
7
14
0
7
7
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
7
0
0
0
0
7
0
0
7
7
7
14
7
% P
% Gln:
7
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% Q
% Arg:
0
7
7
7
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
20
14
0
14
0
0
14
0
7
7
7
0
7
7
7
% S
% Thr:
0
7
0
14
0
7
0
0
7
7
7
14
7
0
0
% T
% Val:
0
0
7
7
14
14
7
14
27
14
7
7
7
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
7
0
0
7
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _