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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
1.52
Human Site:
Y184
Identified Species:
2.38
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
Y184
A
A
K
E
A
A
Q
Y
G
K
K
V
M
V
L
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
D82
L
L
G
Q
A
L
Q
D
S
R
N
Y
G
W
K
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
L106
Q
A
A
L
L
G
G
L
I
Q
D
A
P
H
Y
Dog
Lupus familis
XP_850181
509
55065
S92
H
Q
A
A
L
L
G
S
M
I
R
D
A
P
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
H185
C
I
P
K
K
L
M
H
Q
A
A
L
L
G
Q
Rat
Rattus norvegicus
O89049
498
54218
K81
A
L
L
G
Q
A
L
K
D
S
R
N
Y
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
T171
V
L
D
F
V
T
P
T
P
L
G
N
R
W
G
Chicken
Gallus gallus
NP_001116249
606
66439
H178
C
I
P
K
K
L
M
H
Q
A
A
L
L
G
Q
Frog
Xenopus laevis
NP_001087660
596
65709
H170
C
I
P
K
K
L
M
H
Q
A
A
I
L
G
Q
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
H174
C
I
P
K
K
L
M
H
Q
T
A
L
L
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
L172
V
G
C
I
P
K
K
L
M
H
Q
A
S
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
L194
A
A
K
E
A
S
R
L
G
K
K
V
A
C
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
Y148
V
P
K
K
L
L
V
Y
A
S
K
Y
S
H
E
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
C66
G
T
C
V
N
V
G
C
V
P
K
K
V
M
W
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
C51
G
T
C
V
N
V
G
C
V
P
K
K
V
T
F
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
13.3
6.6
0
N.A.
0
13.3
N.A.
0
0
0
0
N.A.
6.6
N.A.
66.6
N.A.
P-Site Similarity:
100
26.6
13.3
6.6
N.A.
26.6
20
N.A.
0
26.6
26.6
26.6
N.A.
26.6
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
14
7
20
14
0
0
7
20
27
14
14
0
0
% A
% Cys:
27
0
20
0
0
0
0
14
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
0
0
0
0
7
7
0
7
7
0
0
0
% D
% Glu:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
14
7
7
7
0
7
27
0
14
0
7
0
7
34
7
% G
% His:
7
0
0
0
0
0
0
27
0
7
0
0
0
14
7
% H
% Ile:
0
27
0
7
0
0
0
0
7
7
0
7
0
0
0
% I
% Lys:
0
0
20
34
27
7
7
7
0
14
34
14
0
0
7
% K
% Leu:
7
20
7
7
20
47
7
20
0
7
0
20
27
7
20
% L
% Met:
0
0
0
0
0
0
27
0
14
0
0
0
7
7
0
% M
% Asn:
0
0
0
0
14
0
0
0
0
0
7
14
0
0
0
% N
% Pro:
0
7
27
0
7
0
7
0
7
14
0
0
7
7
0
% P
% Gln:
7
7
0
7
7
0
14
0
27
7
7
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
7
0
0
7
14
0
7
0
0
% R
% Ser:
0
0
0
0
0
7
0
7
7
14
0
0
14
0
0
% S
% Thr:
0
14
0
0
0
7
0
7
0
7
0
0
0
7
7
% T
% Val:
20
0
0
14
7
14
7
0
14
0
0
14
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
14
% W
% Tyr:
0
0
0
0
0
0
0
14
0
0
0
14
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _