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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
7.58
Human Site:
Y555
Identified Species:
11.9
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
Y555
N
I
E
V
Y
H
S
Y
F
W
P
L
E
W
T
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
W411
S
Y
F
W
P
L
E
W
T
I
P
S
R
D
N
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
E435
H
A
H
Y
K
P
L
E
F
T
V
A
G
R
D
Dog
Lupus familis
XP_850181
509
55065
L421
Y
H
A
Y
Y
K
P
L
E
F
T
V
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
F519
N
I
E
V
Y
H
S
F
F
W
P
L
E
W
T
Rat
Rattus norvegicus
O89049
498
54218
E410
H
S
F
F
W
P
L
E
W
T
V
P
S
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
Y529
N
I
E
V
Y
H
S
Y
F
W
P
L
E
W
T
Chicken
Gallus gallus
NP_001116249
606
66439
L512
N
L
E
V
Y
H
S
L
F
W
P
L
E
W
T
Frog
Xenopus laevis
NP_001087660
596
65709
L504
N
L
E
V
Y
H
T
L
F
W
P
L
E
W
T
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
L508
N
L
E
V
Y
H
S
L
F
W
P
L
E
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Y502
E
I
E
V
F
H
G
Y
Y
K
P
T
E
F
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
V571
N
I
I
I
Y
H
N
V
F
N
P
L
E
Y
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
D477
A
T
L
S
G
L
P
D
R
V
F
M
K
L
I
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
K395
S
E
K
E
A
I
E
K
Y
G
K
E
N
I
K
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
G380
P
E
A
V
A
K
Y
G
A
E
N
L
K
I
Y
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
93.3
0
N.A.
100
86.6
80
80
N.A.
46.6
N.A.
60
N.A.
P-Site Similarity:
100
20
13.3
20
N.A.
100
20
N.A.
100
93.3
93.3
93.3
N.A.
66.6
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
14
0
14
0
0
0
7
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
14
% D
% Glu:
7
14
47
7
0
0
14
14
7
7
0
7
54
7
0
% E
% Phe:
0
0
14
7
7
0
0
7
54
7
7
0
0
14
7
% F
% Gly:
0
0
0
0
7
0
7
7
0
7
0
0
7
0
0
% G
% His:
14
7
7
0
0
54
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
7
7
0
7
0
0
0
7
0
0
0
14
7
% I
% Lys:
0
0
7
0
7
14
0
7
0
7
7
0
14
0
7
% K
% Leu:
0
20
7
0
0
14
14
27
0
0
0
54
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
47
0
0
0
0
0
7
0
0
7
7
0
7
0
7
% N
% Pro:
7
0
0
0
7
14
14
0
0
0
60
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
0
7
14
7
% R
% Ser:
14
7
0
7
0
0
34
0
0
0
0
7
7
0
0
% S
% Thr:
0
7
0
0
0
0
7
0
7
14
7
7
0
0
47
% T
% Val:
0
0
0
54
0
0
0
7
0
7
14
7
0
0
0
% V
% Trp:
0
0
0
7
7
0
0
7
7
40
0
0
0
34
0
% W
% Tyr:
7
7
0
14
54
0
7
20
14
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _