KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD1
All Species:
18.79
Human Site:
Y572
Identified Species:
29.52
UniProt:
Q16881
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16881
NP_001087240.1
649
70906
Y572
S
R
D
N
N
K
C
Y
A
K
I
I
C
N
T
Chimpanzee
Pan troglodytes
NP_001116141
499
54568
N428
C
Y
A
K
I
I
C
N
T
K
D
N
E
R
V
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
C452
Q
C
Y
V
K
M
V
C
L
R
E
P
P
Q
L
Dog
Lupus familis
XP_850181
509
55065
V438
S
Q
C
Y
V
K
M
V
C
L
R
K
P
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMH6
613
66915
Y536
S
R
D
N
N
K
C
Y
A
K
I
I
C
N
L
Rat
Rattus norvegicus
O89049
498
54218
C427
K
C
Y
A
K
V
I
C
N
L
K
D
N
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507796
621
68478
Y546
S
R
D
N
N
K
C
Y
A
K
I
I
C
N
I
Chicken
Gallus gallus
NP_001116249
606
66439
Y529
G
R
D
N
N
T
C
Y
A
K
I
I
C
N
K
Frog
Xenopus laevis
NP_001087660
596
65709
F521
S
R
D
N
N
T
C
F
A
K
I
I
C
N
K
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
Y525
G
R
D
N
N
K
C
Y
A
K
I
I
C
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
Y519
Q
K
S
V
R
Y
C
Y
L
K
A
V
A
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
C588
E
R
M
D
K
D
H
C
Y
L
K
M
I
C
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42770
565
60834
G494
A
N
T
N
K
V
L
G
V
H
M
C
G
E
D
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
Y412
N
S
K
F
T
A
M
Y
Y
A
M
L
S
E
K
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
A397
S
F
T
A
M
Y
Y
A
M
M
K
P
E
D
K
Conservation
Percent
Protein Identity:
100
76.5
46.5
44.3
N.A.
74.4
70.1
N.A.
72.1
66.5
64.5
64
N.A.
45.9
N.A.
47.8
N.A.
Protein Similarity:
100
76.7
57.9
56.3
N.A.
80.7
73.9
N.A.
82.1
78.4
77.8
77.1
N.A.
59
N.A.
62.9
N.A.
P-Site Identity:
100
13.3
0
13.3
N.A.
93.3
0
N.A.
93.3
80
80
86.6
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
6.6
20
N.A.
93.3
0
N.A.
93.3
80
86.6
86.6
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
27.7
26.5
Protein Similarity:
N.A.
N.A.
N.A.
49.9
44.2
41.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
14
0
7
0
7
40
7
7
0
7
0
0
% A
% Cys:
7
14
7
0
0
0
54
20
7
0
0
7
40
7
0
% C
% Asp:
0
0
40
7
0
7
0
0
0
0
7
7
0
7
7
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
7
0
14
27
0
% E
% Phe:
0
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
0
0
40
40
7
0
7
% I
% Lys:
7
7
7
7
27
34
0
0
0
54
20
7
0
0
34
% K
% Leu:
0
0
0
0
0
0
7
0
14
20
0
7
0
0
20
% L
% Met:
0
0
7
0
7
7
14
0
7
7
14
7
0
0
0
% M
% Asn:
7
7
0
47
40
0
0
7
7
0
0
7
7
40
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
14
14
7
0
% P
% Gln:
14
7
0
0
0
0
0
0
0
0
0
0
0
7
7
% Q
% Arg:
0
47
0
0
7
0
0
0
0
7
7
0
0
7
14
% R
% Ser:
40
7
7
0
0
0
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
0
14
0
7
14
0
0
7
0
0
0
0
0
7
% T
% Val:
0
0
0
14
7
14
7
7
7
0
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
14
7
0
14
7
47
14
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _