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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPD52L1
All Species:
9.39
Human Site:
S122
Identified Species:
22.96
UniProt:
Q16890
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16890
NP_001003395.1
204
22449
S122
S
N
V
G
T
A
I
S
K
K
F
G
D
M
S
Chimpanzee
Pan troglodytes
XP_518724
316
33662
D234
A
I
S
K
K
F
G
D
M
R
S
H
S
I
G
Rhesus Macaque
Macaca mulatta
XP_001107364
316
33853
D234
A
I
S
K
K
F
G
D
M
R
S
H
S
I
G
Dog
Lupus familis
XP_855485
298
32407
S216
S
N
V
G
T
A
I
S
K
K
F
G
D
M
S
Cat
Felis silvestris
Mouse
Mus musculus
O54818
204
22497
S122
N
N
V
G
T
A
I
S
K
K
F
G
D
M
R
Rat
Rattus norvegicus
Q6PCT3
220
23973
T132
L
Y
K
K
T
Q
E
T
L
S
Q
A
G
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507299
318
34409
D195
A
I
S
R
T
F
G
D
M
R
S
H
S
N
H
Chicken
Gallus gallus
Q9I8F4
210
23235
D127
A
I
S
K
K
F
G
D
M
R
S
H
S
I
S
Frog
Xenopus laevis
NP_001087729
192
21153
K110
T
L
S
Q
A
G
L
K
A
T
A
A
I
T
N
Zebra Danio
Brachydanio rerio
NP_001018570
189
20961
Q108
E
T
L
S
T
A
G
Q
R
T
S
A
A
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.5
63.9
64.4
N.A.
90.6
28.6
N.A.
45.2
81.9
67.6
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64.5
63.9
65
N.A.
95
49
N.A.
54.4
88
76.9
74.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
86.6
6.6
N.A.
6.6
6.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
93.3
13.3
N.A.
20
26.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
10
40
0
0
10
0
10
30
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
40
0
0
0
0
30
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
40
0
0
0
0
30
0
0
10
0
% F
% Gly:
0
0
0
30
0
10
50
0
0
0
0
30
10
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
10
% H
% Ile:
0
40
0
0
0
0
30
0
0
0
0
0
10
30
0
% I
% Lys:
0
0
10
40
30
0
0
10
30
30
0
0
0
0
10
% K
% Leu:
10
10
10
0
0
0
10
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
40
0
0
0
0
30
0
% M
% Asn:
10
30
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
10
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
10
40
0
0
0
0
10
% R
% Ser:
20
0
50
10
0
0
0
30
0
10
50
0
40
0
40
% S
% Thr:
10
10
0
0
60
0
0
10
0
20
0
0
0
10
0
% T
% Val:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _