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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMMT All Species: 3.64
Human Site: S193 Identified Species: 10
UniProt: Q16891 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16891 NP_001093639.1 758 83678 S193 S E E A S S S S I R E R P P E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852196 759 83753 T193 A S E E A S S T S V R E R P P
Cat Felis silvestris
Mouse Mus musculus Q8CAQ8 757 83882 V193 E E A F S S S V R E R P P E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511456 534 60219 N47 P E E L A V S N F S E Q K E E
Chicken Gallus gallus NP_001006462 711 79231 I194 A L S S T A R I T L Q A I T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001001401 757 83181 C192 H S A A A E E C C K E C T E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91928 739 81996 A205 P V S K P A A A A A P A P A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_508475 679 75978 T188 A T E A K L K T I N A I N E H
Sea Urchin Strong. purpuratus XP_791544 727 79899 E202 A A S L A A Y E A I V E S C V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 92.4 N.A. 89.9 N.A. N.A. 45.9 72.8 N.A. 58.7 N.A. 25.2 N.A. 27.1 33.2
Protein Similarity: 100 N.A. N.A. 95.9 N.A. 94.1 N.A. N.A. 56.7 83.1 N.A. 74.9 N.A. 45.6 N.A. 49.3 51.7
P-Site Identity: 100 N.A. N.A. 26.6 N.A. 40 N.A. N.A. 33.3 0 N.A. 13.3 N.A. 6.6 N.A. 20 0
P-Site Similarity: 100 N.A. N.A. 46.6 N.A. 40 N.A. N.A. 53.3 33.3 N.A. 26.6 N.A. 26.6 N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 12 23 34 45 34 12 12 23 12 12 23 0 12 23 % A
% Cys: 0 0 0 0 0 0 0 12 12 0 0 12 0 12 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 34 45 12 0 12 12 12 0 12 34 23 0 45 34 % E
% Phe: 0 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 0 0 0 0 0 0 0 12 23 12 0 12 12 0 0 % I
% Lys: 0 0 0 12 12 0 12 0 0 12 0 0 12 0 0 % K
% Leu: 0 12 0 23 0 12 0 0 0 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 12 0 0 12 0 0 % N
% Pro: 23 0 0 0 12 0 0 0 0 0 12 12 34 23 23 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 0 12 12 23 12 12 0 0 % R
% Ser: 12 23 34 12 23 34 45 12 12 12 0 0 12 0 0 % S
% Thr: 0 12 0 0 12 0 0 23 12 0 0 0 12 12 0 % T
% Val: 0 12 0 0 0 12 0 12 0 12 12 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _