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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT16
All Species:
9.39
Human Site:
S187
Identified Species:
18.79
UniProt:
Q17RD7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RD7
NP_114120.2
645
72246
S187
D
D
E
E
L
S
T
S
S
D
S
D
E
E
V
Chimpanzee
Pan troglodytes
XP_522872
645
72300
S187
D
D
E
E
L
S
T
S
S
D
S
D
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001099452
625
69977
V175
T
V
N
G
K
K
Q
V
N
S
F
G
D
D
E
Dog
Lupus familis
XP_547845
645
72205
S187
D
D
E
E
P
C
T
S
S
D
S
D
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN83
639
71236
E187
S
T
S
S
E
S
D
E
D
V
T
K
Q
F
K
Rat
Rattus norvegicus
Q925C0
491
56214
A41
I
Y
H
L
R
D
R
A
R
P
R
L
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509192
645
72314
L189
S
E
S
E
D
E
A
L
S
K
Y
H
E
A
L
Chicken
Gallus gallus
XP_421415
582
64752
A132
E
R
T
G
H
L
V
A
N
G
S
H
W
I
N
Frog
Xenopus laevis
NP_001087543
546
60949
T96
G
K
Y
Q
E
A
M
T
R
L
Y
T
N
R
S
Zebra Danio
Brachydanio rerio
XP_693124
579
63796
G129
E
A
V
S
R
S
Q
G
L
R
G
G
A
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649453
586
64954
V136
A
D
L
Q
R
V
T
V
S
R
D
P
L
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34693
441
49885
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
88.6
N.A.
78.2
23.5
N.A.
40.6
52.5
38.7
38.7
N.A.
30.5
N.A.
21.8
N.A.
Protein Similarity:
100
99.5
95.9
92.4
N.A.
84
39.5
N.A.
57.9
67.4
54.7
56.1
N.A.
48.8
N.A.
39
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
6.6
0
N.A.
20
6.6
0
6.6
N.A.
20
N.A.
0
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
20
13.3
N.A.
33.3
26.6
20
13.3
N.A.
33.3
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
9
9
17
0
0
0
0
9
25
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
34
0
0
9
9
9
0
9
25
9
25
9
17
0
% D
% Glu:
17
9
25
34
17
9
0
9
0
0
0
0
34
25
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
9
0
0
17
0
0
0
9
0
9
9
17
0
0
0
% G
% His:
0
0
9
0
9
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
9
0
0
9
9
0
0
0
9
0
9
0
0
9
% K
% Leu:
0
0
9
9
17
9
0
9
9
9
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
17
0
0
0
9
0
9
% N
% Pro:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
9
% P
% Gln:
0
0
0
17
0
0
17
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
0
0
25
0
9
0
17
17
9
0
9
9
9
% R
% Ser:
17
0
17
17
0
34
0
25
42
9
34
0
0
0
9
% S
% Thr:
9
9
9
0
0
0
34
9
0
0
9
9
0
0
0
% T
% Val:
0
9
9
0
0
9
9
17
0
9
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _