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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT16
All Species:
10.3
Human Site:
T419
Identified Species:
20.61
UniProt:
Q17RD7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RD7
NP_114120.2
645
72246
T419
P
V
F
R
E
K
V
T
F
A
K
L
E
P
R
Chimpanzee
Pan troglodytes
XP_522872
645
72300
T419
P
V
F
R
E
K
I
T
F
A
K
L
E
P
R
Rhesus Macaque
Macaca mulatta
XP_001099452
625
69977
P405
V
T
F
A
K
L
E
P
R
D
V
A
A
C
A
Dog
Lupus familis
XP_547845
645
72205
T419
P
V
F
K
E
K
V
T
F
A
K
L
E
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN83
639
71236
L417
E
K
V
T
F
T
K
L
E
P
R
D
V
A
S
Rat
Rattus norvegicus
Q925C0
491
56214
K271
L
L
P
D
R
K
T
K
H
Q
T
K
V
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509192
645
72314
K421
P
V
F
T
E
T
F
K
F
N
H
V
E
S
E
Chicken
Gallus gallus
XP_421415
582
64752
P362
I
T
F
S
K
L
E
P
H
E
L
G
G
H
A
Frog
Xenopus laevis
NP_001087543
546
60949
S326
F
K
F
N
H
I
E
S
E
M
I
A
N
Y
A
Zebra Danio
Brachydanio rerio
XP_693124
579
63796
S359
F
H
F
S
H
I
E
S
E
M
I
G
N
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649453
586
64954
E366
L
L
H
R
V
N
P
E
D
V
N
N
M
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34693
441
49885
N221
K
V
H
R
K
T
L
N
P
V
F
N
E
T
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
88.6
N.A.
78.2
23.5
N.A.
40.6
52.5
38.7
38.7
N.A.
30.5
N.A.
21.8
N.A.
Protein Similarity:
100
99.5
95.9
92.4
N.A.
84
39.5
N.A.
57.9
67.4
54.7
56.1
N.A.
48.8
N.A.
39
N.A.
P-Site Identity:
100
93.3
6.6
93.3
N.A.
0
13.3
N.A.
40
6.6
6.6
6.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
6.6
20
N.A.
46.6
13.3
13.3
13.3
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
25
0
17
9
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
0
0
0
0
9
9
0
9
0
0
0
% D
% Glu:
9
0
0
0
34
0
34
9
25
9
0
0
42
0
9
% E
% Phe:
17
0
67
0
9
0
9
0
34
0
9
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
9
9
0
% G
% His:
0
9
17
0
17
0
0
0
17
0
9
0
0
17
0
% H
% Ile:
9
0
0
0
0
17
9
0
0
0
17
0
0
0
0
% I
% Lys:
9
17
0
9
25
34
9
17
0
0
25
9
0
0
0
% K
% Leu:
17
17
0
0
0
17
9
9
0
0
9
25
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
9
0
9
0
9
9
17
17
0
0
% N
% Pro:
34
0
9
0
0
0
9
17
9
9
0
0
0
25
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
34
9
0
0
0
9
0
9
0
0
0
34
% R
% Ser:
0
0
0
17
0
0
0
17
0
0
0
0
0
9
9
% S
% Thr:
0
17
0
17
0
25
9
25
0
0
9
0
0
9
0
% T
% Val:
9
42
9
0
9
0
17
0
0
17
9
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _