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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
16.06
Human Site:
S486
Identified Species:
29.44
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S486
P
E
P
D
E
V
M
S
F
Q
S
H
M
T
L
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S486
P
E
P
D
E
V
M
S
F
Q
S
H
M
T
L
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
M485
L
P
E
P
D
E
V
M
S
F
Q
S
H
M
T
Dog
Lupus familis
XP_540093
908
102344
S488
P
E
S
D
N
M
M
S
F
Q
S
Q
M
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
P474
Q
K
S
M
K
N
K
P
K
G
S
H
L
P
E
Rat
Rattus norvegicus
NP_001100187
908
102307
S487
P
E
S
D
D
V
I
S
S
Q
S
L
I
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
T394
S
Q
M
S
L
K
P
T
K
E
T
L
P
L
K
Chicken
Gallus gallus
XP_419963
941
105105
S492
G
E
V
T
N
L
L
S
Q
M
N
F
K
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
K308
G
C
D
E
S
L
W
K
E
Q
R
L
S
I
K
Honey Bee
Apis mellifera
XP_001120033
614
70598
L196
L
E
K
I
E
K
V
L
Q
L
G
R
N
K
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
Y601
S
G
K
V
Q
E
S
Y
S
S
S
E
V
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
I219
L
V
A
M
A
L
L
I
G
S
D
H
D
L
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
R181
K
D
I
K
P
N
S
R
E
P
F
E
C
Y
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
0
66.6
N.A.
13.3
60
N.A.
0
20
N.A.
N.A.
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
100
13.3
73.3
N.A.
33.3
80
N.A.
26.6
40
N.A.
N.A.
N.A.
20
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
8
31
16
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
47
8
8
24
16
0
0
16
8
0
16
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
24
8
8
8
0
0
0
% F
% Gly:
16
8
0
0
0
0
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
31
8
0
16
% H
% Ile:
0
0
8
8
0
0
8
8
0
0
0
0
8
8
0
% I
% Lys:
8
8
16
8
8
16
8
8
16
0
0
0
8
8
16
% K
% Leu:
24
0
0
0
8
24
16
8
0
8
0
24
8
16
39
% L
% Met:
0
0
8
16
0
8
24
8
0
8
0
0
24
8
8
% M
% Asn:
0
0
0
0
16
16
0
0
0
0
8
0
8
8
0
% N
% Pro:
31
8
16
8
8
0
8
8
0
8
0
0
8
8
0
% P
% Gln:
8
8
0
0
8
0
0
0
16
39
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% R
% Ser:
16
0
24
8
8
0
16
39
24
16
47
8
8
8
0
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
8
0
0
31
8
% T
% Val:
0
8
8
8
0
24
16
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _