KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
15.76
Human Site:
S521
Identified Species:
28.89
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S521
D
P
T
L
P
Q
E
S
I
S
A
S
L
N
S
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S521
D
P
T
L
P
Q
E
S
I
S
A
S
L
N
S
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
E520
P
D
S
A
L
P
Q
E
S
I
S
A
S
L
N
Dog
Lupus familis
XP_540093
908
102344
S523
D
G
A
L
P
Q
K
S
I
S
A
S
L
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
N509
P
K
Q
N
P
K
I
N
L
E
N
S
P
D
P
Rat
Rattus norvegicus
NP_001100187
908
102307
S522
D
P
I
L
A
Q
E
S
T
S
P
S
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
T429
E
W
S
T
L
L
A
T
Q
E
P
S
I
S
S
Chicken
Gallus gallus
XP_419963
941
105105
S527
I
C
Q
R
S
T
E
S
K
D
P
V
M
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
P343
I
A
E
F
L
S
E
P
D
T
I
P
N
L
N
Honey Bee
Apis mellifera
XP_001120033
614
70598
K231
E
A
A
M
K
L
F
K
I
N
W
K
T
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
E636
S
E
L
P
V
Q
G
E
V
Q
E
S
T
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
E254
E
I
L
D
K
L
H
E
I
G
K
G
V
Y
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
S216
L
V
G
N
D
Y
D
S
G
G
V
L
G
I
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
0
80
N.A.
13.3
66.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
33.3
86.6
N.A.
40
73.3
N.A.
46.6
26.6
N.A.
N.A.
N.A.
20
40
N.A.
26.6
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
16
8
8
0
8
0
0
0
24
8
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
8
0
8
8
0
8
0
8
8
0
0
0
24
0
% D
% Glu:
24
8
8
0
0
0
39
24
0
16
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
8
0
8
16
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
8
0
0
0
8
0
39
8
8
0
8
8
0
% I
% Lys:
0
8
0
0
16
8
8
8
8
0
8
8
0
0
0
% K
% Leu:
8
0
16
31
24
24
0
0
8
0
0
8
31
16
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
16
0
0
0
8
0
8
8
0
8
24
16
% N
% Pro:
16
24
0
8
31
8
0
8
0
0
24
8
8
0
16
% P
% Gln:
0
0
16
0
0
39
8
0
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
16
0
8
8
0
47
8
31
8
54
8
16
39
% S
% Thr:
0
0
16
8
0
8
0
8
8
8
0
0
16
0
8
% T
% Val:
0
8
0
0
8
0
0
0
8
0
8
8
8
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _