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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
11.82
Human Site:
S547
Identified Species:
21.67
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S547
A
Q
E
Q
F
M
S
S
L
R
P
L
A
I
Q
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S547
A
Q
E
Q
F
M
S
S
L
R
P
L
A
I
Q
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S546
N
V
Q
E
Q
F
M
S
S
P
R
P
L
A
I
Dog
Lupus familis
XP_540093
908
102344
S549
T
Q
E
Y
L
M
S
S
P
R
P
L
A
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
N535
N
S
F
V
S
P
E
N
A
P
C
L
N
L
Q
Rat
Rattus norvegicus
NP_001100187
908
102307
S548
L
Q
E
Q
L
M
P
S
P
R
T
L
A
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
F455
V
S
S
H
S
L
F
F
Q
F
A
E
P
S
A
Chicken
Gallus gallus
XP_419963
941
105105
A553
S
V
G
L
S
L
T
A
S
P
C
L
H
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
L369
I
K
Q
I
G
H
L
L
Q
W
P
E
I
Y
C
Honey Bee
Apis mellifera
XP_001120033
614
70598
G257
S
N
L
C
S
S
C
G
H
S
G
K
I
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
N662
S
D
S
K
T
S
G
N
L
D
S
L
A
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
K280
D
L
P
S
S
S
K
K
S
P
I
K
S
P
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
R242
S
E
D
Q
V
L
E
R
L
Q
D
I
G
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
6.6
66.6
N.A.
13.3
53.3
N.A.
0
13.3
N.A.
N.A.
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
20
73.3
N.A.
26.6
66.6
N.A.
6.6
46.6
N.A.
N.A.
N.A.
20
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
8
8
0
8
0
39
8
8
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
16
0
0
0
8
% C
% Asp:
8
8
8
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
8
31
8
0
0
16
0
0
0
0
16
0
0
0
% E
% Phe:
0
0
8
0
16
8
8
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
8
8
0
0
8
0
8
0
8
% G
% His:
0
0
0
8
0
8
0
0
8
0
0
0
8
0
8
% H
% Ile:
8
0
0
8
0
0
0
0
0
0
8
8
16
16
8
% I
% Lys:
0
8
0
8
0
0
8
8
0
0
0
16
0
0
16
% K
% Leu:
8
8
8
8
16
24
8
8
31
0
0
54
8
16
0
% L
% Met:
0
0
0
0
0
31
8
0
0
0
0
0
0
8
0
% M
% Asn:
16
8
0
0
0
0
0
16
0
0
0
0
8
8
0
% N
% Pro:
0
0
8
0
0
8
8
0
16
31
31
8
8
8
0
% P
% Gln:
0
31
16
31
8
0
0
0
16
8
0
0
0
8
39
% Q
% Arg:
0
0
0
0
0
0
0
8
0
31
8
0
0
0
0
% R
% Ser:
31
16
16
8
39
24
24
39
24
8
8
0
8
8
0
% S
% Thr:
8
0
0
0
8
0
8
0
0
0
8
0
0
0
8
% T
% Val:
8
16
0
8
8
0
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _