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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
14.55
Human Site:
S568
Identified Species:
26.67
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S568
K
S
L
I
S
E
S
S
Q
P
N
T
S
S
H
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S568
K
S
L
I
S
E
S
S
Q
P
N
T
S
S
H
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S567
K
S
L
I
S
E
S
S
Q
P
S
T
S
S
R
Dog
Lupus familis
XP_540093
908
102344
C570
K
S
L
I
P
E
S
C
Q
P
G
T
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
Q556
P
R
T
L
A
I
K
Q
S
K
D
V
S
H
F
Rat
Rattus norvegicus
NP_001100187
908
102307
S569
N
F
L
V
S
E
C
S
Q
P
S
S
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
D476
V
I
A
S
L
Q
L
D
D
I
D
W
E
G
T
Chicken
Gallus gallus
XP_419963
941
105105
T574
S
V
V
P
V
Q
S
T
K
N
S
G
V
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
Q390
I
L
T
R
W
Q
V
Q
Q
S
K
Q
E
K
I
Honey Bee
Apis mellifera
XP_001120033
614
70598
K278
I
D
C
G
T
V
V
K
C
N
N
S
Y
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
L683
K
S
E
G
G
E
L
L
M
K
Q
T
K
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
I301
P
G
S
K
K
N
H
I
K
D
G
C
N
Y
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
D263
G
G
I
K
S
G
D
D
G
E
E
F
R
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
86.6
80
N.A.
6.6
60
N.A.
0
13.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
93.3
80
N.A.
26.6
80
N.A.
13.3
46.6
N.A.
N.A.
N.A.
13.3
20
N.A.
40
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
8
8
8
0
0
8
0
0
8
% C
% Asp:
0
8
0
0
0
0
8
16
8
8
16
0
0
0
0
% D
% Glu:
0
0
8
0
0
47
0
0
0
8
8
0
16
0
16
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
16
0
16
8
8
0
0
8
0
16
8
0
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
31
% H
% Ile:
16
8
8
31
0
8
0
8
0
8
0
0
0
0
8
% I
% Lys:
39
0
0
16
8
0
8
8
16
16
8
0
8
8
0
% K
% Leu:
0
8
39
8
8
0
16
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
16
24
0
8
8
8
% N
% Pro:
16
0
0
8
8
0
0
0
0
39
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
24
0
16
47
0
8
8
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
8
8
8
% R
% Ser:
8
39
8
8
39
0
39
31
8
8
24
16
47
54
8
% S
% Thr:
0
0
16
0
8
0
0
8
0
0
0
39
0
0
8
% T
% Val:
8
8
8
8
8
8
16
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _