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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
9.39
Human Site:
S633
Identified Species:
17.22
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S633
E
N
I
P
E
Q
L
S
C
E
S
E
R
Y
T
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S633
E
N
I
P
E
Q
L
S
C
E
S
E
R
Y
T
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S632
E
N
I
P
E
Q
L
S
C
E
S
E
R
Y
T
Dog
Lupus familis
XP_540093
908
102344
S635
P
A
Q
L
T
C
E
S
E
W
Y
T
T
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
L621
E
S
E
S
S
A
I
L
P
D
F
E
Q
L
S
Rat
Rattus norvegicus
NP_001100187
908
102307
C634
L
S
Y
E
S
E
Q
C
T
L
S
N
K
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
R541
E
F
A
R
D
L
S
R
K
S
S
G
E
H
L
Chicken
Gallus gallus
XP_419963
941
105105
D639
Y
S
G
A
A
Q
S
D
Q
D
H
S
D
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
E455
E
E
L
Y
Y
T
I
E
P
L
D
M
L
E
T
Honey Bee
Apis mellifera
XP_001120033
614
70598
E343
N
E
F
I
A
F
M
E
Q
H
L
S
W
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
K748
H
V
E
T
K
R
T
K
S
R
K
G
R
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
K366
F
P
N
E
E
I
I
K
L
Y
L
S
D
N
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
K328
D
R
D
L
R
E
Q
K
K
T
N
D
W
W
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
100
6.6
N.A.
13.3
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
46.6
33.3
N.A.
26.6
20
N.A.
N.A.
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
16
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
8
24
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
8
0
16
8
8
16
0
0
% D
% Glu:
47
16
16
16
31
16
8
16
8
24
0
31
8
16
0
% E
% Phe:
8
8
8
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
16
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% H
% Ile:
0
0
24
8
0
8
24
0
0
0
0
0
0
8
16
% I
% Lys:
0
0
0
0
8
0
0
24
16
0
8
0
8
0
0
% K
% Leu:
8
0
8
16
0
8
24
8
8
16
16
0
8
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
8
24
8
0
0
0
0
0
0
0
8
8
0
16
8
% N
% Pro:
8
8
0
24
0
0
0
0
16
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
31
16
0
16
0
0
0
8
0
0
% Q
% Arg:
0
8
0
8
8
8
0
8
0
8
0
0
31
0
0
% R
% Ser:
0
24
0
8
16
0
16
31
8
8
39
24
0
8
16
% S
% Thr:
0
0
0
8
8
8
8
0
8
8
0
8
8
0
31
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
16
8
0
% W
% Tyr:
8
0
8
8
8
0
0
0
0
8
8
0
0
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _