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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
12.73
Human Site:
S735
Identified Species:
23.33
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S735
L
Q
N
E
S
R
D
S
K
I
L
K
G
D
Q
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S735
L
Q
N
E
S
R
D
S
K
I
L
K
G
D
Q
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S734
L
Q
N
E
S
R
D
S
K
V
L
K
G
D
Q
Dog
Lupus familis
XP_540093
908
102344
K735
Q
N
E
S
R
K
S
K
V
L
K
G
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
S728
L
H
K
E
S
R
N
S
K
V
L
D
S
R
L
Rat
Rattus norvegicus
NP_001100187
908
102307
F735
S
K
V
L
D
S
H
F
L
Q
E
N
F
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
V640
G
K
S
N
I
P
D
V
Q
R
S
L
A
V
K
Chicken
Gallus gallus
XP_419963
941
105105
G760
S
T
S
L
V
P
S
G
Q
T
T
E
L
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
S554
P
I
T
K
F
L
P
S
D
L
E
S
D
C
D
Honey Bee
Apis mellifera
XP_001120033
614
70598
Q442
E
L
T
S
I
E
P
Q
N
A
V
Q
K
C
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
Q904
S
S
H
L
L
R
G
Q
L
L
S
M
L
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
M466
W
K
R
A
T
R
G
M
N
S
N
M
P
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
H427
L
C
D
Q
Y
E
F
H
S
I
K
C
I
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
93.3
0
N.A.
46.6
0
N.A.
6.6
0
N.A.
N.A.
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
60
6.6
N.A.
33.3
20
N.A.
N.A.
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
16
0
% C
% Asp:
0
0
8
0
8
0
31
0
8
0
0
8
16
24
8
% D
% Glu:
8
0
8
31
0
16
0
0
0
0
16
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
8
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
16
8
0
0
0
8
24
0
0
% G
% His:
0
8
8
0
0
0
8
8
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
16
0
0
0
0
24
0
0
8
0
0
% I
% Lys:
0
24
8
8
0
8
0
8
31
0
16
24
8
8
16
% K
% Leu:
39
8
0
24
8
8
0
0
16
24
31
8
16
8
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
0
% M
% Asn:
0
8
24
8
0
0
8
0
16
0
8
8
0
0
0
% N
% Pro:
8
0
0
0
0
16
16
0
0
0
0
0
8
0
0
% P
% Gln:
8
24
0
8
0
0
0
16
16
8
0
8
0
8
31
% Q
% Arg:
0
0
8
0
8
47
0
0
0
8
0
0
0
16
0
% R
% Ser:
24
8
16
16
31
8
16
39
8
8
16
8
8
16
0
% S
% Thr:
0
8
16
0
8
0
0
0
0
8
8
0
0
0
8
% T
% Val:
0
0
8
0
8
0
0
8
8
16
8
0
0
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _