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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
8.79
Human Site:
S753
Identified Species:
16.11
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S753
E
D
Y
K
V
N
T
S
V
P
Y
S
V
S
N
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S753
E
D
Y
K
V
N
T
S
V
P
Y
S
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S752
E
N
Y
K
V
N
T
S
A
P
Y
S
I
S
N
Dog
Lupus familis
XP_540093
908
102344
V753
N
Y
K
M
N
T
S
V
S
S
T
A
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
P746
C
G
A
N
T
S
L
P
Y
S
F
S
D
K
A
Rat
Rattus norvegicus
NP_001100187
908
102307
E753
L
P
Y
S
F
N
D
E
A
V
K
T
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
E658
S
F
G
H
K
A
S
E
S
L
N
L
E
C
K
Chicken
Gallus gallus
XP_419963
941
105105
K778
E
V
L
P
Q
P
Q
K
P
A
N
V
V
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
K572
F
D
M
S
D
I
V
K
G
I
I
S
N
P
N
Honey Bee
Apis mellifera
XP_001120033
614
70598
R460
V
E
I
F
E
N
A
R
N
V
K
V
K
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
A922
G
D
S
P
M
M
G
A
K
V
L
Q
K
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
E484
T
E
G
E
T
S
S
E
V
V
V
L
D
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
W445
H
Q
S
F
V
I
R
W
R
K
P
K
S
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
80
0
N.A.
6.6
20
N.A.
0
13.3
N.A.
N.A.
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
20
26.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
8
16
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
31
0
0
8
0
8
0
0
0
0
0
16
8
8
% D
% Glu:
31
16
0
8
8
0
0
24
0
0
0
0
8
0
0
% E
% Phe:
8
8
0
16
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
16
0
0
0
8
0
8
0
0
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
16
0
0
0
8
8
0
8
0
0
% I
% Lys:
0
0
8
24
8
0
0
16
8
8
16
8
16
16
8
% K
% Leu:
8
0
8
0
0
0
8
0
0
8
8
16
0
0
8
% L
% Met:
0
0
8
8
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
8
8
39
0
0
8
0
16
0
8
8
31
% N
% Pro:
0
8
0
16
0
8
0
8
8
24
8
0
0
24
16
% P
% Gln:
0
8
0
0
8
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
8
% R
% Ser:
8
0
16
16
0
16
24
24
16
16
0
39
24
31
8
% S
% Thr:
8
0
0
0
16
8
24
0
0
0
8
8
0
8
0
% T
% Val:
8
8
0
0
31
0
8
8
24
31
8
16
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
31
0
0
0
0
0
8
0
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _