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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
22.42
Human Site:
S824
Identified Species:
41.11
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
S824
T
Q
R
M
K
H
S
S
Q
K
H
N
S
S
H
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
S824
T
Q
R
M
K
H
S
S
Q
K
H
N
S
S
H
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S823
T
Q
R
M
K
H
S
S
Q
K
Q
N
T
T
Q
Dog
Lupus familis
XP_540093
908
102344
S824
T
Q
K
M
K
H
S
S
Q
K
H
N
S
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
S817
A
P
E
M
K
H
S
S
Q
K
H
S
L
V
H
Rat
Rattus norvegicus
NP_001100187
908
102307
H824
S
H
N
H
S
L
V
H
D
R
D
S
T
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
S729
I
S
T
A
K
H
Y
S
R
Q
H
N
P
S
Q
Chicken
Gallus gallus
XP_419963
941
105105
T849
F
A
K
K
R
Y
N
T
A
S
I
K
S
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
F643
R
F
S
L
E
D
S
F
D
L
L
V
K
G
D
Honey Bee
Apis mellifera
XP_001120033
614
70598
K531
R
R
I
S
I
T
P
K
R
S
K
I
L
D
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
L993
S
V
K
S
N
T
S
L
E
G
T
N
S
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
S555
L
K
E
A
R
S
R
S
R
K
S
K
T
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
L516
P
D
E
T
E
H
F
L
H
E
K
K
L
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
73.3
80
N.A.
60
0
N.A.
40
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
86.6
93.3
N.A.
66.6
33.3
N.A.
53.3
46.6
N.A.
N.A.
N.A.
20
13.3
N.A.
40
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
16
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
8
0
0
16
0
8
0
0
8
8
% D
% Glu:
0
0
24
0
16
0
0
0
8
8
0
0
0
0
8
% E
% Phe:
8
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
8
0
8
0
54
0
8
8
0
39
0
0
8
24
% H
% Ile:
8
0
8
0
8
0
0
0
0
0
8
8
0
0
0
% I
% Lys:
0
8
24
8
47
0
0
8
0
47
16
24
8
0
0
% K
% Leu:
8
0
0
8
0
8
0
16
0
8
8
0
24
0
8
% L
% Met:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
8
0
0
0
0
47
0
0
8
% N
% Pro:
8
8
0
0
0
0
8
0
0
0
0
0
8
8
8
% P
% Gln:
0
31
0
0
0
0
0
0
39
8
8
0
0
0
24
% Q
% Arg:
16
8
24
0
16
0
8
0
24
8
0
0
0
8
0
% R
% Ser:
16
8
8
16
8
8
54
54
0
16
8
16
39
31
8
% S
% Thr:
31
0
8
8
0
16
0
8
0
0
8
0
24
16
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _