KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
19.09
Human Site:
T405
Identified Species:
35
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
T405
Q
P
I
R
I
V
K
T
R
I
R
N
G
V
H
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
T405
Q
P
I
R
I
V
K
T
R
I
R
N
G
V
H
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
T405
Q
P
I
R
I
V
K
T
R
I
R
N
G
V
H
Dog
Lupus familis
XP_540093
908
102344
S404
Q
P
I
R
I
V
K
S
R
I
R
N
G
I
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
P404
Q
P
I
R
I
V
K
P
R
V
R
N
G
V
H
Rat
Rattus norvegicus
NP_001100187
908
102307
P404
Q
P
I
R
I
V
K
P
R
I
R
N
G
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
V332
K
P
T
E
S
A
V
V
T
V
E
E
E
S
L
Chicken
Gallus gallus
XP_419963
941
105105
T405
Q
A
I
R
I
V
K
T
R
V
K
N
G
I
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
E246
K
L
F
N
K
Y
K
E
T
E
I
L
D
R
M
Honey Bee
Apis mellifera
XP_001120033
614
70598
A134
C
V
Q
G
H
G
E
A
E
A
M
C
A
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
S375
K
S
M
A
T
E
A
S
E
I
N
A
K
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
L157
A
E
A
L
C
A
Q
L
N
N
E
G
H
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
W119
R
N
K
L
F
S
E
W
V
R
E
C
V
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
6.6
66.6
N.A.
N.A.
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
20
86.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
16
8
8
0
8
0
8
8
0
0
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
16
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
8
0
8
16
8
16
8
24
8
8
8
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
8
54
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
39
% H
% Ile:
0
0
54
0
54
0
0
0
0
47
8
0
0
16
0
% I
% Lys:
24
0
8
0
8
0
62
0
0
0
8
0
8
0
0
% K
% Leu:
0
8
0
16
0
0
0
8
0
0
0
8
0
0
24
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
8
0
8
0
0
0
0
8
8
8
54
0
0
0
% N
% Pro:
0
54
0
0
0
0
0
16
0
0
0
0
0
0
8
% P
% Gln:
54
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
54
0
0
0
0
54
8
47
0
0
16
0
% R
% Ser:
0
8
0
0
8
8
0
16
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
0
8
0
0
31
16
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
54
8
8
8
24
0
0
8
47
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _