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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GEN1
All Species:
6.67
Human Site:
T516
Identified Species:
12.22
UniProt:
Q17RS7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q17RS7
NP_001123481.1
908
102884
T516
S
G
I
S
P
D
P
T
L
P
Q
E
S
I
S
Chimpanzee
Pan troglodytes
XP_001136471
908
102886
T516
S
G
I
S
P
D
P
T
L
P
Q
E
S
I
S
Rhesus Macaque
Macaca mulatta
XP_001092312
907
102641
S515
K
L
G
I
S
P
D
S
A
L
P
Q
E
S
I
Dog
Lupus familis
XP_540093
908
102344
A518
L
E
I
T
P
D
G
A
L
P
Q
K
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMI4
908
101761
Q504
T
S
K
A
F
P
K
Q
N
P
K
I
N
L
E
Rat
Rattus norvegicus
NP_001100187
908
102307
I517
L
E
I
S
P
D
P
I
L
A
Q
E
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518788
839
92658
S424
Q
G
K
T
C
E
W
S
T
L
L
A
T
Q
E
Chicken
Gallus gallus
XP_419963
941
105105
Q522
P
P
E
Y
Q
I
C
Q
R
S
T
E
S
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRJ0
726
82516
E338
P
N
E
E
I
I
A
E
F
L
S
E
P
D
T
Honey Bee
Apis mellifera
XP_001120033
614
70598
A226
N
G
V
G
K
E
A
A
M
K
L
F
K
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793916
1102
120745
L631
T
K
I
T
E
S
E
L
P
V
Q
G
E
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169528
638
71262
L249
L
F
D
E
D
E
I
L
D
K
L
H
E
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPD2
599
67201
G211
I
A
I
S
L
L
V
G
N
D
Y
D
S
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.8
79.1
N.A.
70
70
N.A.
35.9
44.4
N.A.
N.A.
N.A.
28.2
27.4
N.A.
25.8
Protein Similarity:
100
99.6
96.9
87.5
N.A.
80.7
80.9
N.A.
50.4
60
N.A.
N.A.
N.A.
44.4
42.6
N.A.
41.7
P-Site Identity:
100
100
0
60
N.A.
6.6
66.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
100
13.3
73.3
N.A.
40
66.6
N.A.
33.3
13.3
N.A.
N.A.
N.A.
13.3
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
25
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
40.9
N.A.
38.1
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
16
16
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
31
8
0
8
8
0
8
0
8
8
% D
% Glu:
0
16
16
16
8
24
8
8
0
0
0
39
24
0
16
% E
% Phe:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
31
8
8
0
0
8
8
0
0
0
8
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
47
8
8
16
8
8
0
0
0
8
0
39
8
% I
% Lys:
8
8
16
0
8
0
8
0
0
16
8
8
8
8
0
% K
% Leu:
24
8
0
0
8
8
0
16
31
24
24
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
16
0
0
0
8
0
8
% N
% Pro:
16
8
0
0
31
16
24
0
8
31
8
0
8
0
0
% P
% Gln:
8
0
0
0
8
0
0
16
0
0
39
8
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
16
8
0
31
8
8
0
16
0
8
8
0
47
8
31
% S
% Thr:
16
0
0
24
0
0
0
16
8
0
8
0
8
8
8
% T
% Val:
0
0
8
0
0
0
8
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _