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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK7
All Species:
17.88
Human Site:
S353
Identified Species:
43.7
UniProt:
Q18PE1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q18PE1
NP_775931.3
504
53097
S353
S
S
Y
S
S
S
L
S
S
Y
A
G
S
S
L
Chimpanzee
Pan troglodytes
XP_001174613
1023
107569
S770
S
S
Y
S
S
S
L
S
S
Y
A
G
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001114786
303
32803
G168
T
R
C
G
Y
W
A
G
V
F
F
L
S
S
A
Dog
Lupus familis
XP_545912
467
47993
R333
G
S
S
L
D
V
W
R
A
G
D
E
F
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q18PE0
504
53158
S353
S
S
Y
S
G
S
F
S
S
Y
A
G
S
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517782
148
16938
N14
Q
Q
L
S
M
W
R
N
F
S
V
L
Q
W
Y
Chicken
Gallus gallus
XP_420818
627
68185
S355
S
S
Y
S
G
S
F
S
S
Y
A
G
S
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686127
643
70150
S371
S
S
Y
S
G
S
F
S
S
Y
T
G
S
M
D
Tiger Blowfish
Takifugu rubipres
Q18PD9
502
53639
S358
S
S
Y
S
G
S
F
S
S
Y
T
G
S
L
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397177
1156
127931
V923
S
H
R
T
A
E
F
V
E
F
E
L
S
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.3
46.8
74.5
N.A.
85.3
N.A.
N.A.
20
55.9
N.A.
45
55.9
N.A.
20
N.A.
N.A.
Protein Similarity:
100
41.7
50
76.9
N.A.
88.4
N.A.
N.A.
24.3
62.8
N.A.
58.3
67
N.A.
28.8
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
80
N.A.
N.A.
6.6
73.3
N.A.
66.6
66.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
26.6
13.3
N.A.
86.6
N.A.
N.A.
13.3
73.3
N.A.
66.6
66.6
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
10
0
40
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
30
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
50
0
10
20
10
0
10
0
0
% F
% Gly:
10
0
0
10
40
0
0
10
0
10
0
60
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
20
0
0
0
0
30
0
30
30
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
10
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
70
70
10
70
20
60
0
60
60
10
0
0
80
30
10
% S
% Thr:
10
0
0
10
0
0
0
0
0
0
20
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
10
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
20
10
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
60
0
10
0
0
0
0
60
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _